Korea Atomic Energy Research Institute

Myung Woo Byun

Sang Hyun Park

Hui Jeong Gwon

Sung Ho Kim

Hae Ran Park

Seung Ho Jang

Sung Tae Yee

Heon Oh

Sung Kee Jo

Disclosed herein is a method for the preparation of radioisotope-labeled compounds using CNT. It comprises filling the carbon nanotube with a radioisotope; and labeling a physiologically active material with the radioisotope charged in the carbon nanotube. Taking advantage of CNT, the method can prepare a radioisotope-labeled compound invention at a high yield and in a simple manner. Also, the radioisotope, when remaining unreacted, can be recovered by the filtration of the CNT, thereby achieving the prevention of radioactive contamination and the reduction of radioactive waste. Further, the radioisotope-labeled compound is useful as a contrast medium for imaging the hepatobiliary system.

Preparation method of radioisotope labeling compound using carbon nanotube

Disclosed relates to an ionic liquid type crown ether derivative, expressed by Chemical Formula 1 below, for isolating metal ions, a method for preparing the same and a method for isolating selectively the metal ions using the cycle size of the same. The present invention can provide the ionic liquid type crown ether and isolate metal ions including radioactive isotopes efficiently using the same. Furthermore, the prevent invention provides crown ether valuably used as a recyclable and environment-friendly isolating medium by preparing crown ether of ionic liquid type.  wherein m, n, Xand R are identical with those in the description.

Ionic liquid type crown ether derivatives, method for preparing the same and method for isolating metal ions using the same

Disclosed relates to organic germanium nanocolloids, to which technetium-99m (Tc), a radionuclide, is labeled, method of the same, and a spleen-imaging agent including the same. According to the invention,Tc-labeled organic germanium nanocolloids having high labeling efficiency and stability can be provided. Moreover, since theTc-labeled organic germanium nanocolloids of the invention are accumulated in the spleen considerably higher than the conventional spleen-imaging agent, it is possible to use theTc-labeled organic germanium nanocolloids of the present invention as a therapeutic radiopharmaceutical for the spleen imaging.

Technetium-99m-labeled organic germanium nanocolloids, method of preparing the same and use thereof

Disclosed is a herbal composition comprising a first hot-water extract from a mixture of the plantsRadix,Makino andMiyabe et Takeda at an equal weight ratio, and a polysaccharide fraction as a precipitate formed by adding ethanol to a second hot-water extract from a mixture of the plantsRadix,Makino andMiyabe et Takeda at an equal weight ratio. The herbal composition of the present invention is effective in improving the anticancer activity, immune response and hematopoiesis of the body, and protecting the body from oxidative damage. Therefore, by stimulating the recovery from the damage to the immune function and hematopoietic function, often occurring during chemotherapy and radiotherapy, and inhibiting oxidative damage, the herbal composition can be applied for the prevention of the side effects of cancer therapy, as well as for the prevention of various degenerative chronic diseases and the improvement of the health of the weak and the elderly.

Herbal composition for improving anticancer activity, immune response and hematopoiesis of the body, and protecting the body from oxidative damage, and the method of preparing the same

Growing community of inventors

Daejeon, South Korea

Myung Woo Byun