University-industry Cooperation Group of Kyung Hee University

Korea Advanced Institute of Science and Technology

Korea Institute of Science and Technology

Seoul National University

Dong-a St Co., Ltd.

Myung Sook Oh

Eunjin Kim

Dae Sik Jang

Youngmi Kim

Byung Hwa Jung

Hocheol Kim

Hak Cheol Kwon

Keon Wook Kang

Hyun Ok Yang

Jeong Hill Park

Mi Won Sohn

Ja Young Ryu

Young Woong Cho

Jin Seok Jeong

Sang Zin Choi

Sung Won Kwon

Doheon Lee

Hyo Geun Kim

Byoung Moon Kim

Hanbyeol Park

Jeong Soo Kim

Xiao Fei Du

Hai Hua Jiang

Seon-Pyo Hong

The present invention relates to a pharmaceutical composition for prevention or treatment of an allergic disease comprising a mixed extract of two or more selected from the group consisting ofroot,root, andas an active ingredient; a method for prevention or treatment of an allergic disease using the pharmaceutical composition; and a health functional food and a feed composition for improvement of an allergic disease. The composition and method of the invention can specifically inhibit the differentiation of Th2 cells and thus can be effectively used as a composition for prevention or treatment of an allergic disease.

Composition for preventing or treating allergic diseases containing mixed extract of two or more amongroot,root, andas active ingredients

The present invention relates to a pharmaceutical composition for treating and preventing degenerative neurological disorders, containing, as an active ingredient, a mixture extract of two or more types selected from the group consisting of Moutan Root Bark, Angelica Dahurica Root, and Bupleurum Root, or a fraction thereof. Specifically, the extract of the mixture of the present invention exhibits a recovery effect on mitochondrial function damage, a relieving effect on endoplasmic reticulum stress and also exhibits simultaneously an inhibitory effect on inflammatory response, which are remarkably improved compared with those exhibited in an in vitro single extract, and the extract of the mixture significantly exhibits an improvement effect on motor coordination and a protective effect on dopaminergic neurons in a Parkinson's disease animal model, and thus the extract of the mixture of the present invention or a fraction thereof can be useful as an active ingredient of a pharmaceutical composition for treating and preventing degenerative neurological disorders.

Pharmaceutical composition containing combination extracts of Moutan Root Bark, Angelica Dahurica Root, bupleurum root or fractions thereof for prevention and treatment of neurodegenerative disorder

Pharmaceutical compositions containing an extract of(THUNB) as an active ingredient for preventing and treating dementia, Parkinson's disease, or epilepsy and methods for using the same. Since the extract ofor the mixture of the extract ofand the extract ofMakino has a cell protection effect and/or a cognition function improved effect in various models including an Amyloid-&#x3b2; induced dementia model, a scopolamine induced dementia model, a 6-hydroxydopamine (6-OHDA) induced Parkinson's disease model, and a Kainic acid induced epilepsy model, the extract ofor the mixture of the extract ofand the extract ofMakino may be used as the pharmaceutical composition for preventing and treating dementia, Parkinson's disease, or epilepsy and in health foods for preventing and treating dementia, Parkinson's disease, or epilepsy.

Pharmaceutical composition containing extract of houttuynia cordata as active ingredient for preventing and treating dementia, parkinson's disease, or epilepsy

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Seoul, South Korea

Myung Sook Oh