Yuhan Corporation

Myung-Hun Cha

Young-Ae Yoon

Dong-Hoon Kim

Tae-Kyun Kim

Hyun-Joo Lee

Jae-Young Sim

Tai-Au Lee

Eun-Jung Jung

Kyoung-Kyu Ahn

Jae-Gyu Kim

Suk-Won Yoon

Byung-Nak Ahn

Hyouk-Woo Lee

Sun-Young Jang

Chan-Sun Park

Heui-Il Kang

Seok-Hee Han

Heui Ii Kang

Choong-Hyun Lee

The present invention provides a diaminopyrimidine derivative or its pharmaceutically acceptable salt, a process for the preparation thereof, a pharmaceutical composition comprising the same, and a use thereof. The diaminopyrimidine derivative or its pharmaceutically acceptable salt functions as a 5-HTreceptor agonist, and therefore can be usefully applied for preventing or treating dysfunction in gastrointestinal motility, one of the gastrointestinal diseases, such as gastroesophageal reflux disease (GERD), constipation, irritable bowel syndrome (IBS), dyspepsia, post-operative ileus, delayed gastric emptying, gastroparesis, intestinal pseudo-obstruction, drug-induced delayed transit, or diabetic gastric atony.

Diaminopyrimidine derivatives and processes for the preparation thereof

The present invention provides novel pyrrolo[2,3-c]pyridine derivatives or pharmaceutically acceptable salts thereof, processes for the preparation thereof, and compositions comprising the same. The pyrrolo[2,3-c]pyridine derivatives or pharmaceutically acceptable salts thereof of the present invention have excellent proton pump inhibition effects and possess the ability to attain a reversible proton pump inhibitory effect.

Pyrrolo[2,3-C]pyridine derivatives and processes for the preparation thereof

Pyrrolo[2,3-c]pyridine derivatives and processes for the preparation thereof

The present invention provides novel pyrrolo[3,2-b]pyridine derivatives or pharmaceutically acceptable salts thereof, processes for the preparation thereof, and compositions comprising the same. The pyrrolo[3,2-b]pyridine derivatives or pharmaceutically acceptable salts thereof of the present invention have excellent proton pump inhibition effects and possess the ability to attain a reversible proton pump inhibitory effect.

Pyrrolo[3,2-B]pyridine derivatives and processes for the preparation thereof

Growing community of inventors

Hwaseong-si, South Korea

Myung-Hun Cha