Commissariat a L'energie Atomique Et Aux Energies Alternatives

Biomerieux, Inc.

Centre National De La Recherche Scientifique

Université Grenoble Alpes

Avalun

Elimaje

Myriam-Laure Cubizolles

Patrick Pouteau

Cédric Allier

Vincent Poher

Christine Peponnet

Johanna Spiaczka

Jean-Philippe Charrier

Frederic Revol-Cavalier

Agnès Dupont-Filliard

Florence Rivera

Marie-Hélène Charles

Lucie Baujard-Lamotte

Véronique Lanet

Patrice Caillat

Cedric Allier

Thomas Bordy

Jean Berthier

Jean-Guillaume Coutard

Magalie Faivre

Maxime Huet

Claude Vauchier

Frédéric Revol-Cavalier

Laurent Veron

Remco Den Dulk

Manuel Alessio

Marie-Line Cosnier

Arnaud Buhot

Yoann Roupioz

Nadège Nief

Vivian Aubert

David Rabaud

Cedric Poulain

Patricia Laurent

Cédric Poulain

Gwenola Sabatte

Magali Faivre

The invention relates to a method for detecting an analyte present in a liquid specimen, including: injecting the liquid specimen into a detection chamber, the detection chamber having a non-zero volume enclosing polymeric beads covered with a reagent suitable for the analyte to be detected; capturing at least one image of at least one region of the detection chamber using a sensor; processing the image acquired by the sensor, which includes determining a texture level of the acquired image; and determining a concentration of the analyte depending on the texture level determined for the image.

Method and system for detecting an analyte present in a liquid specimen

A system for preparing a calibrated volume of blood plasma that includes a plurality of parts: a device for preparing the calibrated volume of blood plasma, which is in the form of a single card; a pneumatic-type actuating system SP; a treatment and command unit UC configured such as to execute a command sequence of different pneumatic command points of the pneumatic actuation system with a view to obtaining, from a taken blood sample, the calibrated volume of blood plasma. The device includes three distinct modules: a fluidic connection module Monto which a blood sampling device may be connected; a module Mfor separation of the blood plasma contained in the blood sample; a module Mfor obtaining at least one calibrated volume of blood plasma, after separation.

Device for preparing a calibrated volume of blood plasma

The present invention relates to a method of obtaining peptides from procaryotic and/or eucaryotic cells.

Method for obtaining peptides

The method is provided for characterizing agglomeration of particles in a liquid containing an analyte, including introducing liquid into a fluid chamber; mixing the liquid with a bifunctional reagent, lighting the fluid chamber using an excitation light beam extending through the fluid chamber in a longitudinal direction (X); acquiring at least one image using a matrix photodetector, each image including pixels (I(x,y), x,y representing the coordinates of a pixel of an image, the image (I(x,y)) being formed by radiation transmitted by the lighted fluid chamber; and calculating from at least one acquired image (I(x,y)), at least one indicator (Ind) characterizing the particle agglomeration. The photodetector can be positioned less than 1 cm from the fluid chamber, and during the calculation step, the calculated indicator (Ind) is representative of the intensity of the pixels of the image. The method advantageously allows for characterizing the agglomeration of particles in a liquid.

Method and system for characterizing the agglomeration or speed of particles contained in a liquid, such as blood particles

The invention is a method for characterizing a liquid sample, said liquid sample containing particles, the method comprising the following steps: The method comprises, prior to step c), applying an acoustic wave to the sample, said acoustic wave forming pressure nodes and pressure antinodes in the sample, so as to separate, in the latter, a poor portion, poor in particles, and rich portion, rich in particles, such that, in step c), the sample is characterized:

Method for characterizing a liquid sample containing particles

This method for estimating the quantity of an analyte contained in a liquid includes the following steps:

Method and system for estimating the quantity of an analyte contained in a liquid

The method according to the invention is capable of characterizing a variation in the speed of particles or agglomeration of particles, the particles, such as blood particles, being contained in a liquid (). The characterization method includes the following steps: During the acquisition step, the photodetector () is positioned at a distance (D) smaller than 1 cm from the fluid chamber () in the longitudinal direction (X).

Method and system for characterizing the movement speed of particles contained in a liquid, such as blood particles

A method of counting thrombocytes contained in a sample of blood, the method having the steps: Apparatus for implementing the method.

Method and apparatus for counting thrombocytes

The present invention relates to a method for assaying catalytic plasma enzymes, such as transaminases and NADH-dependent enzymes, in a sample of whole blood, by measuring, in a microfluidic chamber, the decrease in the fluorescence of NADH consumed during the enzymatic reactions catalyzed by the NADH-dependent enzymes.

Method for assaying plasma enzymes in whole blood

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Corenc, France

Myriam-Laure Cubizolles