Other

Kaken Pharmaceutical Company, Ltd.

Rikagaku Kenkyusho

Kaken Kagaku Kabushiki Kaisha

Rikagaku Kenkyusho Wako

Mutsuyuki Kochi

Setsuo Takeuchi

Shinichiro Esumi

Makoto Yamamoto

Akira Kawarada

Yukio Inoue

Tsuneo Saita

Keiji Sekine

Kaguya Sasaki

Shozo Kawabata

As a result of research work and investigations relating to the effect of benzaldehyde on cell membranes, it was found that benzaldehyde has high activity in the treatment of selected malignant conditions. Based on this finding, we have now completed the present invention directed to a composition comprising benzaldehyde as the active ingredient. This composition is effective against selected malignant conditions which are carcinoma of the colon, cancer of the stomach, cancer of the tongue, peritonitis carcinomatosa, cancer of the liver and malignancies induced by SF.sub.40 virus.

Composition and method of treating selected malignant conditions

Disclosed is a novel carcinostatic composition comprising 4,6-0-benzylidene-D-glucopyranose as the active ingredient. This active ingredient exerts a very high carcinostatic activity according to a specific carcinostatic mechanism quite different from that of conventional carcinostatic chemotherapeutic agents. The active ingredient is very low in toxicity and is highly stable and water-soluble. This composition is effective against selected malignant conditions which are carcinoma of the colon, cancer of the stomach, cancer of the tongue, peritonitis carcinomatosa, cancer of the liver and malignancies induced by SV.sub.40 virus.

A composition and method of treating selected malignant conditions

A pharmaceutical composition for retarding and reducing cachexia comprising, as an efficacious ingredient, at least one compound selected from the group consisting of benzaldehyde and 4,6-O-benzylidene-D-glucose, and a method for retarding and reducing cachexia in humans which comprises administering to an affected human at least one said compound.

Pharmaceutical composition for retarding and reducing cachexia

Growing community of inventors

Matsudo, Japan

Mutsuyuki Kochi