Sankyo Company, Limited

Mitsui Toatsu Chemicals, Incorporated

Mutsuo Nakajima

Tatsuo Haneishi

Akio Torikata

Takao Okazaki

Mamoru Arai

Seigo Iwado

Ryuzo Enokita

Ryuzou Enokita

Kohei Furuya

Katsuhiko Kawakubo

Kiyoshi Koi

Atsushi Hagimura

Manbu Tohjigamori

Toshiaki Katayama

Hiroshi Kimura

Takeshi Kinoshita

Shuji Takahashi

Kiyoshi Hamano

Masatoshi Inukai

Yo Takiguchi

Hideyuki Haruyama

Hisaharu Kuboyama

Kunio Nishihara

Kenji Yoshida

Osamu Ando

Sadao Sato

Tadashi Komiyama

Ikuo Inage

Masaki Nakahara

Sadao Sata

Akira Sato

Yasuyuki Takamatsu

Yasuhiro Itoh

5-Amino-1-(hydroxymethyl)cyclopentane-1,2,3,4-tetraol and 2-amino-4-(hydroxymethyl)-3a,5,6,6a-tetrahydro-4H-cyclopent[d]oxazole-4,5, 6-triol, which have the ability to inhibit the activity of sugar hydrolases, especially .beta.-glucosidase and sucrase and can thus be used for the treatment and prophylaxis of tumorous conditions, AIDS, diabetes and obesity, can be prepared by hydrolysis of trehazolin. 2-Amino-4-(hydroxymethyl)-3a,5,6,6a-tetrahydro-4H-cyclopent[d]oxazole-4,5, 6-triol can also be prepared by fermentation using newly isolated strains Micromonospora sp. SANK 62390, FERM BP-3521 and Amycolatopsis sp. SANK 60791, FERM BP-3513.

Polyhydroxycyclopentane derivatives, their preparation and their

A multi-layered electrostrictive effect element comprises films or thin plates of an electrostrictive material and inner electrodes alternatively arranged in layers, the inner electrodes being formed on the entire surface of the films or thin plates of the electrostrictive material, wherein the insulating layer which insulates the inner electrodes exposed on the side end faces of the element comprises a polyimide resin having repeating units represented by the following general formula (I): ##STR1## (wherein X represents a tetravalent group selected from the group consisting of tetravalent phenyl groups; tetravalent biphenyl groups; and tetravalent polyphenyl groups in which at least one of either the phenyl or bipheny groups are bonded through at least one member selected from the group consisting of O, CO, S, CH.sub.2, C(CH.sub.3).sub.2 and C(CF.sub.3).sub.2 and Y represents a bivalent groups selected from the group consisting of bivalent phenyl groups; bivalent biphenyl groups; bivalent polyphenyl groups in which at least one of either the phenyl or biphenyl groups are bonded through at least one member selected from the group consisting of O, CO, S, SO.sub.2, CH.sub.2, C(CH.sub.3).sub.2 and C(CF.sub.3).sub.2 ; alkylene groups; and xylylene groups) and an insulating filler. A process for making a multi-layered electrorestrictive effect element having a high dielectric strength is also disclosed.

Multi-layered electrostrictive effect element

A new compound, named Substance No. 51262, may be produced by cultivating a suitable microorganism of the genus Streptomyces, especially the new strain SANK 63584 (FERM BP-958). Said compound has herbicidal and growth retardant properties. Said compound has the following structural formula: ##STR1##

Process for the production of an imidazoledione compound by a strain of

Novel compounds, called chloropolysporins B and C, and salts thereof have antibiotic properties and would appear to be members of the class of glycopeptide antibiotics containing chlorine. They may be produced by cultivating a suitable strain of microorganism of the genus Micropolyspora, especially Micropolyspora sp. SANK 60983 (FERM BP-538). They may be combined with conventional pharmaceutically acceptable carriers or diluents for therapeutic use or incorporated into edible excipients, such as feed or water, for use as a growth-promoting agent, especially for farm animals.

Antibiotics called 'chloropolysporins B and C', a process for their

A novel compound names 'cornexistin' has the formula (I): ##STR1## and it and the corresponding ring-opened diacid and salts thereof have herbicidal and growth regulating effects. Cornexistin can be prepared by cultivation of a microorganism of the genus Paecilomyces, e.g. Paecilomyces variotii Bainier SANK 21086.

Herbicide, its preparation and use

The present invention relates to a longitudinally effective piezoelectric element exhibiting a large displacement at low voltage and to a ceramic composition suitable for producing the longitudinally effective piezoelectric element.

Piezoelectric element with giant electrostrictive effect and ceramic

Imidazoledione compounds useful as herbicides

Novel compounds, called chloropolysporins B and C, and salts thereof have antibiotic properties and would appear to be members of the class of glycopeptide antibiotics containing chlorine. They may be produced by cultivating a suitable strain of miroorganism of the genus Micropolyspora, especially Micropolyspora sp. SANK 60983 (FERM BP-538). They may be combined with conventional pharmaceutically acceptable carriers or diluents for therapeutic use or incorporated into edible excipients, such as feed or water, for use as a growth-promoting agent, especially for farm animals.

Antibiotics called `chloropolysporins B and C`, a process for their

A novel compound named 'cornexistin' has the formula (I): ##STR1## and it and the corresponding ring-opened diacid and salts thereof have herbicidal and growth regulating effects. Cornexistin can be prepared by cultivation of a microorganism of the genus Paecilomyces, e.g. Paecilomyces variotii Bainier SANK 21086.

Anhydride herbicides

Ethylene is oxidized into ethylene oxide by bringing a feed gas mixture, which contains the ethylene, oxygen and at least 1 vol. % of carbon dioxide as well as at least 0.5 vol. ppm of a chlorine-containing burning reaction decelerator and at least 1 vol. ppm as calculated in terms of nitrogen monoxide of a nitrogen oxide and/or a precursor thereof, into contact with a catalyst which carries silver and as a practically sole alkali metal, rubidium at an Rb/Ag atomic ratio of 2/1000-7/1000 on a fire-resistant carrier having a specific surface area of 1 m.sup.2 /g or smaller.

Preparation process of ethylene oxide

A novel compound, called chloropolysporin, has antibiotic properties and would appear to be a member of the class of glycopeptide antibiotics containing chlorine. It may be produced by cultivating a suitable strain of microorganism of the genus Micropolyspora, especially Micropolyspora sp. SANK 60983 (FERM BP-538). It may be combined with conventional pharmaceutically acceptable carriers or diluents for therapeutic use or incorporated into edible excipients, such as feed or water, for use as a growth-promoting agent, especially for farm animals.

Antibiotic called 'chloropolysporin', a process for its preparation, and

Macrolide antibiotics are derivatives of the compound Mycoplanecin and have the formula: ##STR1## (in which R represents a hydrogen atom or an N-(.alpha.-hydroxybutyryl)-N-methylvalyl group). The compound in which R represents an N-(.alpha.-hydroxybutyryl)-N-methylvalyl group can be prepared by reducing Mycoplanecin and the compound in which R represents a hydrogen atom can be prepared by the hydrolysis of Mycoplanecin or of the compound of formula (I) in which R represents an N-(.alpha.-hydroxybutyryl)-N-methylvalyl group.

Macrolide antibiotic

Mycoplanecin derivatives of formula (I): ##STR1## [wherein: R represents a hydrogen atom, an N-(.alpha.-ketobutyryl)-N-methylvalyl group or an N-(.alpha.-hydroxybutyryl)-N-methylvalyl group;

Mycoplanecin derivatives and their preparation

A novel antibiotic substance, named 'Mycoplanecin', of presently unknown structural formula, is produced by cultivating a Mycoplanecin-producing microorganism of the genus Actinoplanes, especially the Actinoplanes nov. sp. Strain No. 41042, NRRL No. 11462.

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Tokyo, Japan

Mutsuo Nakajima