Becton Dickinson and Company Limited

Novartis Ag

Alcon, Inc.

Alcon Laboratories, Inc.

Alcon Manufacturing, Ltd.

Alcon Research, Ltd.

Alcon Universal Ltd.

Mutlu Karakelle

Xin Hong

Xiaoxiao Zhang

Robert A Taller

Albert R Leboeuf

Douglas Schlueter

Michael John Simpson

Joseph I Weinschenk, Iii

Charles Freeman

David E Spielvogel

Richard J Zdrahala

John W Sheets, Jr

Min-Shiu Lee

Stephen J Van Noy

Yan Zhang

Chance Lehman

Diana M Cordova

Houshang Karimi

Michael J Simpson

Donald D Solomon

Mohammad A Khan

Myoung-Taek Choi

Yueai Liu

David Jinkerson

Anilbhai S Patel

Daniel Robert Carson

Kwan Y Chan

Costin Eugene Curatu

Myoung Choi

Krishnakumar Venkateswaran

C David Benson

Joseph I Weinschenk

John M Yanni

David L Meadows

Robert A Scott

David Anthony Downer

Gustav Graff

Arthur Bradley

Son Trung Tran

Albert R LeBoeuf

Son C Tran

Sushant P Muchhala

Robert D Angelopoulos

Stanley C Wells

Kamal K Das

Richard W Beck

Qiwen Zhan

David L Jinkerson

Jihong Xie

Xioaxioa Zhang

Theo O Onwunaka

Alex Sacharoff

Carl D Benson

Joseph D Menczel

Min-Shui Lee

Dan Stanley

Michael R Brunstedt

Michael Simpson

Iii Joseph I Weinschenk

An ophthalmic lens system comprises a lens body with a curved outer surface and an assembly including a plurality of spaced apart nanostructures. The assembly covers at least a portion of the curved outer surface.

Optical structures with nanostructre features and methods of use and manufacture

In one aspect, the present invention provides an ophthalmic lens (e.g., an IOL) that includes an optic having an anterior surface and a posterior surface disposed about an optical axis. At least one of the surfaces (e.g., the anterior surface) has a profile characterized by superposition of a base profile and an auxiliary profile. The auxiliary profile can include an inner region, an outer region and a transition region between the inner and the outer regions, where an optical path difference across the transition region (i.e., the optical path difference between the inner and the outer radial boundaries of the transition region) corresponds to a non-integer fraction (e.g., &#xbd;) of a design wavelength (e.g., a wavelength or about 550 nm).

Extended depth of focus (EDOF) lens to increase pseudo-accommodation by utilizing pupil dynamics

An ophthalmic lens includes an optical filter operable to filter out at least visible light having a wavelength less than 450 nm. The lens also includes a first diffractive structure adapted to produce a focus for visible light in a first wavelength range above 550 nm and to reduce longitudinal chromatic aberration to less than one diopter for incoming visible light in the first wavelength range. The lens also includes a second diffractive structure outside the first diffractive structure in a radial direction and adapted to produce a focus for visible light in a second wavelength range between 450 nm and 550 nm. The second diffractive structure is also adapted to reduce longitudinal chromatic aberration for incoming visible light in the second wavelength range to less than one diopter while allowing longitudinal chromatic aberration in the first wavelength range in an amount greater than the first diffractive structure.

IOL with varying correction of chromatic aberration

An accommodating intraocular lens (AIOL) includes an optic adapted to produce a trapezoidal phase shift and a plurality of haptics. Each haptic extends from a haptic-optic junction to at least one transverse arm contacting a capsular bag of the eye, and each haptic has sufficient length and rigidity to stretch a capsular bag of the eye to contact ciliary muscles of the eye. The haptic-optic junctions vault the optic forward relative to the haptics and compression of the haptics by the ciliary muscles moves the anterior optic forward. A combined accommodative power produced by the motion of the anterior optic and the trapezoidal phase shift is at least 0.5 Diopters.

Accommodating intraocular lens using trapezoidal phase shift

In one aspect, the present invention provides a method of designing an intraocular lens (IOL) to address variations of at least one ocular parameter in a population of patient eyes. The method can include establishing at least one eye model in which the ocular parameter can be varied over a range exhibited by the population. The eye model can be employed to evaluate a plurality of IOL designs in correcting visual acuity for eyes in the patient population. An IOL design that provides a best fit for visual performance over at least a portion of the parameter range can then be selected.

Correction of higher order aberrations in intraocular lenses

An intraocular lens (IOL) delivery device is disclosed. The device includes an intraocular lens cartridge having an internal coating wherein the coating includes a polymeric material that is compatible with a polymeric material of a material that forms the cartridge. Preferably, the polymeric material of the coating, the cartridge or both is a polyurethane material.

Intraocular lens delivery device having a cartridge with an internal coating

A diffractive multifocal design for ocular implant is provided. This ocular implant includes a diffractive multifocal intraocular lens (IOL) and a number of haptics. The diffractive multifocal IOL passes optical energy to distance, intermediate and near foci. The haptics mechanically couple to the diffractive multifocal IOL in order to position and secure the diffractive multifocal IOL within the eye. The diffractive multifocal IOL may include both a diffractive region and a refractive region, the diffractive multifocal IOL operable to phase shift optical energy such that constructive interference occurs within the diffractive region and the refractive region.

Phase-shifted center-distance diffractive design for ocular implant

In one aspect, the present invention provides an ophthalmic lens (e.g., an IOL) that includes an optic having an anterior surface and a posterior surface disposed about an optical axis. At least one of the surfaces (e.g., the anterior surface) has a profile characterized by superposition of a base profile and an auxiliary profile. The auxiliary profile can include an inner region, an outer region and a transition region between the inner and the outer regions, where an optical path difference across the transition region (i.e., the optical path difference between the inner and the outer radial boundaries of the transition region) corresponds to a non-integer fraction (e.g., &#xbd;) of a design wavelength (e.g., a wavelength of about 550 nm).

In certain embodiments, an ophthalmic lens comprises an optic. The optic has an optical axis and surfaces comprising an anterior surface and a posterior surface. At least one of the surfaces has an inner refractive region and a refractive-diffractive structure disposed outwardly from the inner refractive region in a direction away from the optical axis. The inner refractive region is adapted to contribute refractively to a distance focus optical power. The refractive-diffractive structure comprises one or more diffractive regions and one or more refractive regions. A diffractive region is adapted to contribute diffractively to a multi-zone optical power, and a refractive region is adapted to contribute refractively to the distance focus optical power.

Apodized hybrid diffractive-refractive IOL for pseudo-accommodation

In one aspect, the present invention provides a method for correcting vision that employs two lenses, at least one of which is a multifocal lens, with different focusing characteristics for use in the two eyes of the patient. The visual performance of each lens (e.g., visual contrast or acuity) is selected in accordance with a predefined relation so as to optimize the binocular visual performance provided by the combination of the lenses.

Alternating optical system: mixing and matching optics to maximize binocular visual benefits

An improved multifocal design for an ocular implant is provided. This ocular implant includes an intraocular lens (IOL) and a number of haptics. The IOL passes optical energy. A microstructure within the IOL places the IOL under tension. The microstructure is operable to be broken in a controlled manner to release tension in the IOL and reshape the IOL. This may be done at any time post operatively and in conjunction with wavefront aberrometry to provide improved results. The haptics mechanically couple to the IOL in order to position and secure the IOL within the eye.

Non-invasive power adjustable intraocular lens

In one aspect, the present invention provides a method of correcting vision, which comprises determining a residual accommodation exhibited by a natural, crystalline lens of an eye, and selecting a multifocal intraocular lens (IOL), which exhibits a far-focus optical power (e.g., in a range of about &#x2212;15 to about +50 Diopters (D)) and an add power (e.g., in a range of about 1 D to about 4 D), for implantation in the eye while retaining the natural lens. The add power of the IOL is selected as a function of the residual accommodation such that a combination of the IOL and the natural lens provides a visual contrast greater than about 10% at a spatial frequency of about 20 cycles/degree for viewing objects at a distance greater than about 30 cm from the eye.

Intermediate vision with phakic multifocal optics utilizing residual accommodations

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Fort Worth, TX, United States of America

Mutlu Karakelle