Ethicon, Gmbh

Agency for Science, Technology and Research

Ethicon Endo-surgery, Inc.

Indigo Medical, Inc.

Cordis Corporation

Johnson and Johnson Vision Care, Inc.

Cordis Neurovascular, Inc.

Advanced Technologies and Regenerative Medicine, LLC

Endo-surgery, Inc.

Murty Narayan Vyakarnam

Mark B Roller

Kevin L Cooper

Angelo G Scopelianos

Mark C Zimmerman

David V Gorky

Sriram Natarajan

Hong Yee Low

Chee Tiong Lim

Isabel Rodriguez

Frederick E Shelton, IV

Yufu Li

Iksoo Chun

Mora Carolynne Melican

Joseph J Hammer

Audrey Yoke Yee Ho

Juan A Lorenzo

Joseph Henry Contiliano

Shawn Thayer Huxel

Zhigang Li

Richard Champion Davis, Iii

Kelly R Brown

Noha Elmouelhi

David A Dalessandro

Emma Kim Luong-Van

Jie Jenny Yuan

Clairene A Bazilio

Randall Braxton Pugh

Rao S Bezwada

Vladimir Mitelberg

Donald K Jones

Darren R Sherman

Anna Gosiewska

Alireza Rezania

Joel S Rosenblatt

Leslie Hamilton

Arindam Datta

Lowell G Saferstein

Zohra Fadli

Hiep Quang Do

Jenny J Yuan

James F Martin

Ram L Kataria

John McAllen, Iii

Dhanuraj S Shetty

Thomas Patrick Hyland

Isabel Rodriquez

Angelo G Scopellianos

Mcallen Iii John John

A staple cartridge for stapling the tissue of a patient is disclosed. The staple cartridge comprises a cartridge body, a plurality of staples, and a compressible tissue thickness compensator configured to adapt in thickness in response to the thickness of the tissue and adaptively apply different pressures to the tissue based on the thickness of the tissue captured within the staples. The compressible tissue thickness compensator comprises a plurality of fibers comprising a first matrix oriented in a first direction and a second matrix oriented in a second direction that is different than the first direction. A network of interstices is defined intermediate and among the first matrix and the second matrix. The network of interstices comprises a plurality of cavities that promote tissue and cellular ingrowth between the first and second matrices of fibers.

Tissue thickness compensator comprising tissue ingrowth features

An implant having an adhesive structure comprising a planar surface having two sides and rectangular cuboid-based protrusions having pyramidal tips extending from at least one of said sides, optionally having a porous basic supporting structure, and methods of making and using such implants.

Adhesive structure with tissue piercing protrusions on its surface

A stapling system for stapling tissue is disclosed. The stapling system comprises a cartridge body, staples removably stored in the cartridge body, and an implantable layer. The implantable layer comprises a first portion comprising a first density, wherein the first portion is comprised of a material. The implantable layer further comprises a lattice comprising a second density, wherein the first density is different than the second density, and wherein the lattice is comprised of the material. The implantable layer further comprises a medicament which promotes tissue ingrowth into the layer in a specified pattern.

Retainer assembly including a tissue thickness compensator

A polydioxanone film comprising substantially cylindrical polydioxanone pillars on at least one side thereof, said pillars having diameters from about 0.2 &#x3bc;m to about 3 &#x3bc;m, and heights from about 2 &#x3bc;m to about 20 &#x3bc;m from the surface of the film, a process for adsorbing proteins using the film and medical devices incorporating the film.

Super-hydrophilic structures

In various embodiments, a compensator can be attachable to an anvil of a fastening instrument. The compensator can comprise a support layer configured to be attached to the anvil and a scaffold attached to the support layer. In at least one embodiment, the scaffold can comprise a plurality of scaffold layers comprised of a biocompatible material and a plurality of cavities, wherein the layers and the cavities can define a matrix favorable to tissue and cellular ingrowth.

This invention discloses methods and apparatus for providing an ophthalmic lens with a textured pattern within an optic zone and an ophthalmic lens with a textured pattern within the optic zone.

Surface enhanced ophthalmic lens

A laminate and process of making the laminate is disclosed comprising: a surgical mesh having first and second surfaces; and an adhesive structure having adhesive and non-adhesive surfaces, wherein the non-adhesive surface of the adhesive structure is laminated to at least one of said first and second surfaces of said surgical mesh, and the adhesive surface of said adhesive structure has protrusions extending therefrom comprising a resin having a Young's modulus of greater than 17 MPa, which protrusions are of sufficiently low diameter to promote adhesion by increasing physical attractive forces between the adhesive structure and a target surface, as measured by shear adhesion.

Adhesive structure with stiff protrusions on adhesive surface

A blood clotting substrate and device which has a plurality of oxygen plasma-treated polypropylene pillars extending from the surface of a polypropylene film.

Blood clotting substrate and medical device

The present invention relates to a medical device for placement at a predetermined location within a passageway of the human body, and more particularly, relates to a flexible embolization device which may be delivered by a catheter to a pre-selected position within a blood vessel to thereby embolize a blood vessel or a blood vessel defect, such as an aneurysm or fistula. Specifically, the embolization device comprises an elongated coil having a lumen, the coil and lumen being at least partially embedded in an elongated foam member comprising, in some embodiments, a flexible, biodegradable, water insoluble, open, interconnecting-cell foam material having embolic characteristics, and capable of allowing cell proliferation into the open cell foam interior.

Foam matrix embolization device

The present invention relates to tissue scaffold implant devices useful in the repair and/or regeneration of diseased and/or damaged musculoskeletal tissue and that include a tissue scaffold component fixedly attached to a scaffold fixation component via a polymeric adhesive layer, and to methods of making such tissue scaffold implant devices.

Attachment of absorbable tissue scaffolds to fixation devices

A polymeric coating is applied to at least one embolic coil carried in a fixture, at least a portion of said embolic coil being generally vertical and straight. The coil is carried in the fixture during the processing, and may remain in the fixture if desired for further steps of processing.

Method of making active embolic coil

The present patent describes a biocompatible composite made of a first fibrous layer attached to a three-dimensional inter-connected open cell porous foams that have a gradient in composition and/or microstructure through one or more directions. These composites can be made from blends of absorbable and biocompatible polymers. These biocompatible composites are particularly well suited to tissue engineering applications and can be designed to mimic tissue transition or interface zones.

Foam composite for the repair or regeneration of tissue

The present invention is directed to reinforced, biocompatible, biodegradable compositions suitable for use in implantable medical devices and medical devices made at least in part from such compositions, where the compositions include a biocompatible, biodegradable polymer; a biocompatible, biodegradable wax; and greater than about 30 weight percent of an inorganic filler material.

Reinforced implantable medical devices

The present invention is a synthetic, biocompatible, bioabsorbable, porous foam tissue scaffolds possessing physicochemical properties suitable for use in the repair and regeneration of dermal tissue and to methods of preparing the foam scaffold.

Porous tissue scaffolds for the repair and regeneration of dermal tissue

A biocompatible tissue implant, as well as methods for making and using such an implant, is provided. Preferably, the tissue implant is bioabsorbable. The tissue implant comprises one or more layers of a bioabsorbable polymeric foam having pores with an open cell structure. The tissue implant also includes a reinforcement component which contributes both to the mechanical and the handling properties of the implant. Preferably, the reinforcement component is bioabsorbable as well. The tissue implant provided can be used in connection with the surgical repair of soft tissue injury, such as injury to the pelvic floor.

Reinforced tissue implants and methods of manufacture and use

Growing community of inventors

New York, NY, United States of America

Murty Narayan Vyakarnam