Barnes-hind Pharmaceuticals, Inc.

Barnes-hind, Inc.

Pilkington Visioncare Holdings, Inc.

Murray J Sibley

Gordon H Yung

Petronio D Urrea

Rebecca F Nite

Jack Hramchenko

Dinesh Ochhavlal Shah

Hans H Kaspar

A composition is disclosed useful for cleaning hard and soft contact lenses, in which cleansing action is provided by a relatively soft abradant particulate sparingly soluble room temperature solid organic acid or inorganic salt, preferably in combination with one or more surfactants. The particulate material effectively removes deposits from the lens, and readily dissolves on the application of water.

Method for cleaning contact lens with dissolving abradant

A contact lens is disinfected in an aqueous H.sub.2 O.sub.2 solution. The H.sub.2 O.sub.2 solution is neutralized and transformed in situ into a buffered, saline storage solution by adding a neutralizer such as sodium sulfite or sodium thiosulfate, and optional buffering agents. The neutralizer has a coating which dissolves to release the ingredients only a period of time after it is added, so that it can be put into the H.sub.2 O.sub.2 solution at the same time that the lens is.

Disinfection of contact lenses

An aqueous or gel cleaning composition is provided which comprises approximately by weight (a) 0.02 to 25.0% of at least one nonionic cleaner; (b) 0.01 to 10% of a diglycol carbonate monomer; (c) 0.01-10.0% of an antifog agent; (d) up to 25% of a lower aliphatic alcohol; (e) up to 1.0% of a preservative agent; (f) the balance water and if a gel is desired 0.1 to 5.0% of a thixotropic gelling agent.

Cleaning compositions

Methods and compositions are provided for the treatment of dry eye and discontinuous tear films. The ophthalmic solution for maintaining a continuous tear film employs a combination of hydroxyalkylcellulose and polyvinyl alcohol in a predetermined ratio in an aqueous isotonic medium.

Treatment of dry eye

Method and compositions are provided for the effective cleaning of soft and silicone contact lenses by soaking the lenses for a time sufficient to remove adherent residues in a solution containing an epoxy modified silicone surfactant and a fatty acid amide (or nitrogen analog thereof) surfactant, which may be cationic or non-ionic. Other additives may also be included such as thickening agents, bactericides, salts, anionic surfactants, and the like. The compositions are found to be particularly effective in removing strongly adhering proteinaceous matter, as well as lipids and polysaccharides. By employing a particular combination of surfactants, soft contact lenses can be freed of impurities and adhering matter introduced during manufacture of the lens, while the lens is being hydrated. The lens is soaked under moderate conditions in an aqueous saline bath with a combination of a zwitterion surfactant and a fatty acid amide surfactant.

Cleaning agents for contact lenses

Method and compositions are provided for elevated temperature disinfection of soft contact lenses. The lenses are heated at a temperature and for a time sufficient to provide disinfection in an aqueous stabilized saline solution having a small amount of a non-eye-irritating neutral surfactant. Particularly effective are N-hydroxyalkylated fatty acid amides.

Composition and method treating soft contact lenses at elevated

Improved water soluble abradant skin cleanser is provided comprising in a nonoleaginous hydrous cream base a sparingly soluble relatively soft nontoxic, nonirritating particulate salt or sugar, a nonirritating, nontoxic surfactant as a stable cream base, employing at least one derivative of sulfuric acid, e.g. sulfate ester salt or sulfonate and water. In a preferred embodiment, borax is combined with a substantial amount of an alkyleneoxy sulfate ester salt or taurate salt and a small amount of water. The cleanser aids in the treatment of oily skin, acne and scalp conditions.

Abradant skin cleanser

Compositions are provided for the effective cleaning of soft and silicone contact lenses by soaking the lenses for a time sufficient to remove adherent residues in a solution containing an epoxy modified silicone surfactant and a fatty acid amide (or nitrogen analog thereof) surfactant, which may be cationic or non-ionic. Other additives may also be included such as thickening agents, bactericides, salts, anionic surfactants, and the like. The compositions are found to be particularly effective in removing strongly adhering proteinaceous matter, as well as lipids and polysaccharides.

Improved water soluble abradant skin cleanser is provided comprising in a non-oleaginous hydrous cream base a sparingly soluble relatively soft non-toxic non-irritating particulate salt, a non-irritating, non-toxic surfactant as a stable cream base, employing at least one derivative of sulfuric acid, e.g. sulfate ester salt or sulfonate and water. In a preferred embodiment, borax is combined with a substantial amount of an alkyleneoxy sulfate ester salt or tauride salt and a small amount of water. The cleanser aids in the treatment of oily skin, acne and scalp conditions.

Growing community of inventors

Berkeley, CA, United States of America

Murray J Sibley