Korea Institute of Science and Technology

Murale Dhiraj

Jun Seok Lee

Ji Hyeon Yun

Chang No Yoon

Seong Cheol Hong

Provided are a labelling agent including a compound of the following Formula 1, a labelling composition, a method of labelling a protein with the labelling agent, and a method of detecting the protein using the labelling agent: wherein R, R, R, R, R, R, and Rare independently H, substituted or unsubstituted &#x2014;C-alkyl-, &#x2014;C-alkenyl, or &#x2014;C-alkynyl, Ris H or &#x2014;NRR, Rand Rare independently H, substituted or unsubstituted &#x2014;C-alkyl-, &#x2014;C-alkenyl, or &#x2014;C-alkynyl, X is &#x2014;NR, &#x2014;O, or S, Ris H, substituted or unsubstituted &#x2014;C-alkyl-, &#x2014;C-alkenyl, or &#x2014;C-alkynyl, Y is &#x2014;ORor &#x2014;NRR, Ris H, substituted or unsubstituted &#x2014;C-alkyl-, &#x2014;C-alkenyl, or &#x2014;C-alkynyl, and Rand Rare independently H, substituted or unsubstituted &#x2014;C-alkyl-, &#x2014;C-alkenyl, or &#x2014;C-alkynyl.

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Seoul, South Korea

Murale Dhiraj