Aurigene Discovery Technologies Limited

Um Pharmauji Sdn. Bhd.

Muni Kumar Mahadari

Subramanya Hosahalli

Sunil Kumar Panigrahi

Mohamed Takhi

Chandrashekar Reddy Kottam

Noorsaadah Abd Rahman

Rohana Yusof

The present invention provides substituted pyridine derivatives of formula (I), which may be therapeutically useful as as anti-bacterial agents, more particularly FabI inhibitors. Formula (I) in which R1 to R5 and L have the meanings given in the specification, and pharmaceutically acceptable salts thereof that are useful in the treatment and prevention in diseases or disorder, in particular their use in diseases or disorder where there is an advantage anti-bacterial agents, more particularly FabI inhibitors. The present invention also provides methods for synthesizing and administering the FabI inhibitor compounds. The present invention also provides pharmaceutical formulations comprising at least one of the FabI inhibitor compounds together with a pharmaceutically acceptable carrier, diluent or excipient therefor. 

Substituted pyridine derivatives as FabI inhibitors

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Gadwal, India

Muni Kumar Mahadari