Orchid Chemicals & Pharmaceuticals Limited

Mukut Gohain

Sriram K Rajagopal

Senthilkumar Udayampalayam Palanisamy

Andrew Gnanaprakasam

Maneesh Paul-Satyaseela

Sathishkumar Devarajan

Panchapakesan Ganapathy

Venkatasubramanian Hariharan

Shakti Singh Solanki

Novel 2-substituted methyl penam derivatives include the formula (I), their analogs, their tautomeric forms, their stereoisomers, their polymorphs, their solvates, their pharmaceutically acceptable salts, and pharmaceutical compositions containing them; wherein A=C or N; Het is a three- to seven-membered heterocyclic ring; Rrepresents carboxylate anion, or &#x2014;COORwhere Rrepresents hydrogen, carboxylic acid protecting group or a pharmaceutically acceptable salt; Rand Rmay be same or different and independently represent hydrogen, halogen, amino, alkyl, protected amino, optionally substituted alkyl, alkenyl, alkynyl and the like; R represents substituted or unsubstituted alkyl, alkenyl, aryl, aralkyl, cycloalkyl, heterocyclyl or heterocyclylalkyl.

2-substituted methyl penam derivatives

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Chennai, India

Mukut Gohain