Ranbaxy Laboratories, Inc.

Indian Oil Corporation Limited

Coraltree, Inc.

Mukesh Kumar Sharma

Naresh Kumar

Jag Mohan Khanna

Pankaj Sharma

Chandrahas Khanduri

Swargam Sathyanarayan

Girij Pal Singh

Alok Sharma

Chandra Has Khanduri

Mukesh Kumar Madhra

Mohammed Salman Hashmi

Tiruvali S Srinivasan

Hari Mohan Sriram

Gaurav Bajaj

Keshav Srinivasan

Rajneesh Maurya

The present invention provides to a process for recovery of an organic compound (i.e. Ethanol, propanol, butanol, Acetone, iso-propyl alcohol) from a fermented broth which is produced from different fermentation technologies. The present invention particularly relates to an integrated process for ethanol separation from the fermentation broth using integrated vapor compressing unit (turbofans), evaporator (falling film) and a broth stripper column (vacuum distillation system). The process is operated under low temperature for the separation and recovery of the organic compound (particularly ethanol) from the fermented broth containing live microbes typically below or at 50&#xb0; C. to ensure the activity of the microbes in the broth recycle. Again, the activity of the microbes is further ensured by maintaining the residence time of the microbe containing broth outside the Fermentor is less than or equal to 10 minutes.

Integrated process for ethanol separation from fermented broth for low temperature applications

Embodiments of the present invention include a method and system for sharing changes made by an application to a file on one computer, coherently with other computers, over the Internet. If the application changes multiple files (also referred to as a file group), changes made to all the files are shared together coherently with other computers over the Internet. Coherence over multiple file copies and file group copies is maintained whether users work on files online or offline. A 'File Upload Lock' is maintained on a Cloud Server for ensuring coherent sharing of changes made to files. Embodiments include two file syncing processes, variously described as 'Incremental File Upload' or &#x2018;Incremental File Download&#x2019; and &#x2018;Delta File Upload&#x2019; or &#x2018;Delta File Download&#x2019;. Embodiments also encompass an &#x2018;Explorer&#x2019; software tool and user interface that displays folders and files on user devices with pertinent details from the device and the Cloud Server.

System and method for file sharing and updating

The present invention relates to processes for reducing impurities in lacosamide during the preparation of lacosamide. The invention provides processes for minimizing or removing impurities such as (2R)-2-(acetylamino)-3-(benzylamino)-3-oxopropyl acetate of Formula II or (2R)-2-propanoylamino-N-benzyl-3-methoxypropionamide of Formula III in lacosamide. 

Processes for reducing impurities in lacosamide

The present invention provides a novel process for the preparation of pure valganciclovir hydrochloride.

Process for the preparation of valganciclovir hydrochloride

A multistep process for producing 8-chloro-6-(2-fluorophenyl)-1-methyl-4-H-imidazo�1,5a!�1,4!benzodiazepine (midazolam) comprises treating a compound of Formula II with a lower alkyl dithiol to produce a compound of Formula III, wherein n=2 or 3, converting the compound of Formula III to a compound of Formula VII, and then treating the compound of Formula VII with a deprotecting agent, thereby producing midazolam. Novel intermediate compounds are also disclosed.

Process for the manufacture of

A multistep process for producing 8-chloro-6-(2-fluorophenyl)-1-methyl-4-H-imidazo�1,5a!�1,4! benzodiazepine (midazolam) comprises treating a compound of Formula II with a lower alkyl dithiol to produce a compound of Formula III, wherein n=2 or 3, converting the compound of Formula III to a compound of Formula VII, and then treating the compound of Formula VII with a deprotecting agent, thereby producing midazolam. Novel intermediate compounds are also disclosed.

Process for the manufacture of 8-chloro-6 (2-fluorophenyl)-1

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New Delhi, India

Mukesh Kumar Sharma