King Fahd University of Petroleum and Minerals

King Saud University

King Abdulaziz City for Science and Technology

Muhammad Altaf

Anvarhusein Abdulkadir Isab

Said S Al-Jaroudi

Ali Alhoshani

Adam Ahmed Abdallah Seliman

Abdulaziz Al-Saadi

Muhammad Ali Ehsan

Mohammed Yagoub Jomaa

Khalid Omer

Muhammad Monim-Ul-Mehboob

Adam A A Sulaiman

Anvar Husain Abdul Kadir Isab

Mohammed Ismail Wazeer

Manzar Sohail

Saleh Abdulaziz Altuwaijri

Ali Osman Altoum

A zinc-based metal organic framework and method of making is described. The zinc-based metal organic framework is in the form of an interpenetrating diamondoid framework where each Znion center is linked with four other Znion centers in a distorted tetrahedral geometry. The linking occurs through diamine and dicarboxylic acid linkers. The zinc-based metal organic framework may be deposited on a transparent conducting film and used as a photoelectrode for photoelectrochemical water splitting.

Water stable zinc-based metal organic framework and method of use

The invention is directed to platinum(II) complexes comprising dithiocarbamates and methods for treating cancer using these complexes.

Pharmaceutical composition containing a cisplatin and platinum thiocyanate combination

Method for administering cisplatin and a thiocyanate complex to treat ovarian cancer

Platinum(II) complexes with various selenones (L) having the general formula PtL(NH)Xare disclosed. The platinum(II) complexes inhibit growth of cancer cells in vitro and are useful for treatment of proliferative disorders such as cancers and/or tumors.

Anticancer trans-diaminoplatinum(II) complexes of selenones

Gold(I) complexes and gold(I) dithiocarbamate polymers as anticancer therapeutics. The Au(I) ion within the gold(I) complexes is coordinated to two phosphine ligands. The repeating unit formed by Au(I) ion coordinating to dithiocarbamate ligands are connected by Au(I)&#x2014;Au(I) interactions within the gold(I) dithiocarbamate polymers. Also disclosed are methods of synthesis, pharmaceutical compositions incorporating the gold(I) complexes, pharmaceutical compositions incorporating the gold(I) dithiocarbamate polymers, and methods of treating cancer.

Method of treating cancer with a two-component anti-cancer composition

Synthesis, x-ray structures and cytotoxic behavior of platinum (II) complexes of dithiocarbamates

Gold(I) complexes and gold(I) dithiocarbamate polymers as anticancer therapeutics. The Au(I) ion within the gold(I) complexes is coordinated to two phosphine ligands. The repeating unit formed by Au(I) ion coordinating to dithiocarbamte ligands are connected by Au(I)-Au(I) interactions within the gold(I) dithiocarbamate polymers. Also disclosed are methods of synthesis, pharmaceutical compositions incorporating the gold(I) complexes, pharmaceutical compositions incorporating the gold(I) dithiocarbamate polymers, and methods of treating cancer.

Two-component anti-cancer composition

Gold(III) complexes containing mixed ligands. A method of treating cancer with these complexes is disclosed. The complexes are cytotoxic to prostate, breast, ovarian, and Hodgkin lymphoma cancer cell lines. These complexes were either more potent than cisplatin or had similar potency to cisplatin.

Gold(III) complexes as anticancer agents and a method of treating cancer

Platinum(II) complexes with various selones (L) having the general formula PtLClare disclosed. The platinum(II) complexes of the invention inhibit growth of cancer cells in vitro and are useful for treatment of proliferative disorders such as cancers and/or tumors.

Platinum(II) complexes with selone ligands and method of use

Gold(I) complexes and gold(I) dithiocarbamate polymers as anticancer therapeutics. The Au(I) ion within the gold(I) complexes is coordinated to two phosphine ligands. The repeating unit formed by Au(I) ion coordinating to dithiocarbamate ligands are connected by Au(I)-Au(I) interactions within the gold(I) dithiocarbamate polymers. Also disclosed are methods of synthesis, pharmaceutical compositions incorporating the gold(I) complexes, pharmaceutical compositions incorporating the gold(I) dithiocarbamate polymers, and methods of treating cancer.

Gold(I) complexes, pharmaceutical compositions thereof, and methods of treating cancer

Gold(I) complex with mixed ligands as an anticancer agent. The gold(I) ion is coordinated to a dithiocarbamate ligand and a phosphorus-containing ligand (e.g. phosphines). Also described are a pharmaceutical composition incorporating the gold(I) complex, a methods of synthesizing the gold(I) complex, and a method for treating cancer.

Gold complex-containing cancer activity composition

DNA/Dithiocarbamato phosphine metal complex

Mononucleotide-dithiocarbamate complex

Cancer cell-containing composition

Gold(I) complexes as antiproliferative or antitumor agents. The gold(I) ion is connected to a N-heterocyclic carbene and further coordinated to a selone ligand. Also described are a pharmaceutical composition incorporating the gold(I) complex, a method of synthesizing the gold(I) complex, and a method for treating a proliferative disorder (e.g. cancer)

Growing community of inventors

Dhahran, Saudi Arabia

Muhammad Altaf