Industrial Technology Research Institute

Muh-Lan Chen

Jui-Hsiang Chen

Yu-Hua Chen

Bin-Hong Tsai

Mei-Jung Liu

Shu-Hua Jan

Hsuen-Tseng Chang

Shu-Fang Jiang

Jian-Hong Chen

Mao-Song Lee

Andrew Teh Hu

Jeng Wei

Yu-Der Lee

Chung-Yi Chang

Herng-Dar Hwu

Ho-May Lin

Ru-Fong Laiw

Shu-Chieh Liuo

Fan-Yen Lee

Hung-Yuan Hsu

Teh Hu

The description provides a biodegradable hyaluronic acid derivative including at least one modified hyaluronic acid repeating unit represented by the formula (HA)-[O(C&#x2550;O)NH-M]p, wherein HA is a unit including N-acetyl-D-glucosamine and D-glucuronic acid, M is a modifying moiety containing a Chydrocarbyl group, and p is an integer of 1 to 4.

Biodegradable hyaluronic acid derivative

The invention provides a biodegradable hyaluronic acid derivative including at least one modified hyaluronic acid repeating unit represented by the formula (HA)-[O(C&#x2550;O)NH-M]p, wherein HA is a unit including N-acetyl-D-glucosamine and D-glucuronic acid, M is a modifying moiety containing a Chydrocarbyl group, and p is an integer of 1 to 4.

Biodegradable hyaluronic acid derivative, biodegradable polymeric micelle composition and pharmaceutical or bioactive composition

A biodegradable hyaluronic acid derivative comprising a modified hyaluronic acid repeating unit represented by the formula (HA)-[O(C&#x2550;O)NH-M], wherein HA is a unit including N-acetyl-D-glucosamine and D-glucuronic acid, M is a modifying moiety containing a Chydrocarbyl group or a prepolymer, and p is an integer of 1 to 4. The biodegradable hyaluronic acid derivative when dissolved in a hydrophilic medium can form micelles and can be used to entrap a pharmaceutically active or bioactive molecule.

Biodegradable hyaluronic acid derivative and biodegradable polymeric micelle composition

A biodegradable copolymer with a core block comprising bioresorbable hydrophobic polyester segment and from 3 to 10 shell blocks comprising hydrophilic polyethylene glycol segment. The hydrophobic polyester segment and each of the hydrophilic polyethylene glycol segments are linked by a urethane linkage. A polymeric micelle composition containing the copolymer is also provided. The copolymer forms micelles when the concentration of the copolymer in a dispersing medium reaches or exceeds the critical micelle concentration. The micelles possess good drug and bioactive agent delivery characteristics and are suitable for use in drug delivery or cosmetic applications.

Biodegradable copolymer, and polymeric micelle composition containing the same

A porous polyurethane tube suitable for use as a vascular graft prosthesis is prepared by placing solvent type polyurethane resin coated mandrel in a static coagulant consisting of water, ethanol and optionally aprotic solvent within 30 seconds immediately after the coating step, separating the tube by placing the mandrel in a swelling agent containing at least 90 percent by weight of ethanol and rinsing with a solution containing at least 80 percent by weight ethanol.

Method for preparing a porous polyurethane vascular graft prosthesis

A composition of matter including a polymeric material which is either a plastic having carbon to carbon linkages or a binary blend of the plastic and starch, in which the plastic is at least 25% by weight of the binary blend; and an organic peracid compound dispersed in the polymeric material, the quantity of the peracid compound being 0.1 to 10% by weight of the polymeric material.

Degradable plastics

Growing community of inventors

Hsinchu, Taiwan

Muh-Lan Chen