Asana Biosciences, LLC

Takeda Pharmaceutical Company Limited

Abs Development 1, Inc.

Mrinalkanti Kundu

Scott Kevin Thompson

Ashis K Saha

Tony Priestley

Suvadeep Nath

Tsuyoshi Maekawa

Keiko Kakegawa

Minoru Yoshida

Shizuo Kasai

Jumpei Aida

Hideyuki Igawa

Asato Kina

Uttam Khamrai

The present disclosure provides novel compounds and methods for preparing and using these compounds. In one embodiment, the compounds are of the structure of formula (I), wherein R-Rare defined herein. In a further embodiment, these compounds are useful in method for regulating one or both of the P2Xor P2Xreceptors. In another embodiment, these compounds are useful for treating pain in patients by administering one or more of the compounds to a patient. In another embodiment, these compounds are useful for treating respiratory dysfunction in patients by administering one or more of the compounds to a patient.

P2X3 and/or P2X2/3 compounds and methods

The present disclosure provides novel compounds and methods for preparing and using these compounds. In one embodiment, the compounds are of the structure of formula (I), wherein R-Rare defined herein. In a further embodiment, these compounds are useful in method for regulating one or both of the P2Xor P2Xreceptors. In another embodiment, these compounds are useful for treating pain in patients by administering one or more of the compounds to a patient. In another embodiment, these compounds are useful for treating respiratory dysfunction in patients by administering one or more of the compounds to a patient. 

P2Xand/or P2Xcompounds and methods

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The present invention provides an aromatic ring compound having a melanin-concentrating hormone receptor antagonistic action and useful as an agent for the prophylaxis or treatment of obesity and the like. The present invention relates to a compound represented by the formula wherein each symbol as defined in the specification, or a salt thereof.

Benzimidazole derivatives as MCH receptor antagonists

Growing community of inventors

West Bengal, India

Mrinalkanti Kundu