International Business Machines Corporation

Mpho Mokoatle

Darlington Shingirirai Mapiye

James Junior Mashiyane

Gciniwe Dlamini

Stephanie Julia Muller

Dineo Andronicah Makoro

In an approach to automatically downsampling DNA sequence data using variational autoencoders and preserving genomic integrity of an original file embodiments execute, by an encoder, bootstrapping on genomic sequence data to produce resamples. Furthermore, embodiments assess, by the encoder, unrepresentativeness and self-inconsistency of the resamples and selecting a representative resample according to the assessment, and build, by a modified encoder, vector representations from genotype likelihoods based on the selected representative sample. Additionally, embodiments integrate, by an analytics engine, mapping positional information and the genotype likelihoods to identify an optimum vector representation of a resample, and decode, by a modified decoder, the identified optimum vector representation of the resample to obtain a down-sampled read file that resembles and maintains the genomic integrity of the original file.

Downsampling genomic sequence data

A method for non-invasive detection of ingested medication which provide for one or more processors to receive images of medications designated for a user prior to ingestion of the medications by the user. The one or more processors capture an ultrasound image during ingestion by the user by an ultrasound device removably adhered to a throat area of the user. The one or more processors determine whether contents of the ingestion by the user includes one or more of the medications designated for the user, and responsive to determining the contents of the ingestion by the user includes one or more of the medications designated for the user, the one or more processors generate a confirmation that includes identification of the detected medications ingested by the user.

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Orkney, South Africa

Mpho Mokoatle