Wyeth

Isp Investments Inc.

Pfizer Corporation

Mousumi Ghosh

Panolil C Raveendranath

Mahmut Levent

Ronald Stanley Michalak

Christoph Martin Dehnhardt

Jianxin Ren

Michael William Winkley

Charles Guinosso

Frederick J Vyverberg

Ara R Boyajian

Michel Cantin

Alan Stockton

Osama M Musa

Michael A Tallon

Donald I Prettypaul

Anita Wai-Yin Chan

Joseph Zeldis

Hani M Fares

Yanzhong Wu

Arkadiy Zinoviy Rubezhov

Drupesh Patel

Krishnamurthy Nacharaju

Karen Sutherland

Christoph Dehnhardt

Ronald S Michalak

The invention provides non-aqueous compositions comprising film forming polymers comprising repeating units derived from: (a) at least one monomer comprising at least one functionalized or unfunctionalized acryloyl moiety and at least one lactam moiety; (b) at least one monomer selected from the group consisting of functionalized and unfunctionalized C-Calkyl (alk)acrylates, C-Calkyl (alk)acrylamides, and combinations thereof; and (c) at least one monomer selected from the group consisting of functionalized and unfunctionalized C-Calkyl (alk)acrylates, C-C(alk)alkyl acrylamides, and combinations thereof. The invention further provides applications of these compositions in various industrial arts, particularly in personal care. The invention furthermore provides water-resistant non-aqueous personal care compositions. Variables a, b and c are described herein. 

Non-aqueous compositions of polymers derived from monomers having acryloyl moiety and lactam moiety and applications thereof

The invention provides polymers comprising repeating units derived from (a) from 16% by weight to about 35% by weight of said polymer of at least one N-vinyl lactam monomer; (b) at least one monomer selected from the group consisting of functionalized and unfunctionalized C-Calkyl (meth)acrylates, C-Calkyl (meth)acrylamides and combinations thereof; and (c) at least one monomer selected from the group consisting of functionalized and unfunctionalized C-Cbranched alkyl (meth)acrylates, C-Cbranched alkyl (meth)acrylamides, and combinations thereof; wherein the polymer has a glass transition temperature of greater than about 45&#xb0; C. The invention further provides various compositions, such as, personal care, sun care, coatings, and pharmaceutical compositions comprising the polymers described herein. The invention furthermore provides water-resistant sun care compositions comprising the polymers described herein. Subscripts x, y and z are described herein. (Formula (I)) 

Vinyl lactam-derived polymers, compositions thereof having enhanced water-resistance, and methods of use thereof

The present invention provides a compound of formula 1: wherein Ris CF, Ris H' Ris H.

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The present invention provides method for making a compound of formula 1: comprising the steps of reacting compounds of formulas 2 and 3: to produce a compound of formula 4: wherein R, R, R, Rand Rare defined as described herein. The compound of formula 4 is then converted to the compound of formula 1. The invention further comprises compounds of formulas 3 and 4 and methods for making compounds of formulas 3 and 4.

Processes for preparing sulfonamide trifluoroalkyl substituted alcohol compounds are provided. Desirably, the compounds are heterocyclic sulfonamide trifluoroalkyl substituted alcohol compounds or phenyl sulfonamide trifluoroalkyl substituted alcohol compounds.

Selective N-sulfonylation of 2-amino fluoro- and trifluoroalkyl substituted alcohols

Processes for preparing amino alcohols or salts thereof and sulfonamide substituted alcohol compounds are provided. Desirably, the sulfonamide substituted alcohol compounds are heterocyclic sulfonamide trifluoroalkyl-substituted alcohol compounds or phenyl sulfonamide trifluoroalkyl-substituted alcohol compounds.

Methods for preparing sulfonamide substituted alcohols and intermediates thereof

A process for making a compound of formula I and intermediate compounds thereof, wherein Ris CN, F or Cl; Ris H or Br; and Rand Rare each independently H or F. The compounds of formula I are useful in the treatment of chronic inflammatory diseases, such as rheumatoid arthritis.

Process for the synthesis of 3-(3-fluoro-4-hydroxyphenyl)-7-hydroxynaphthonitrile

The present invention provides processes for the preparation of arylalkylsulfonyl halides and heteroarylalkylsufonyl halides of Formula I: Ar&#x2014;R&#x2014;SO&#x2014;X, that are useful as intermediates in the preparation of pharmaceuticals.

Processes for the preparation of aryl- and heteroaryl-alkylsulfonyl halides

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Elmwood Park, NJ, United States of America

Mousumi Ghosh