Takeda Chemical Industries, Inc.

Motoo Hozumi

Yoshio Yoshioka

Hiroaki Nomura

Susumu Tsushima

New carbamic acid esters, inclusive of salts thereof, which have the formula: ##STR1## wherein n is zero or 1; R.sup.1 and R.sup.2 independently represent --H, --OCH.sub.3 or --OCONHR.sup.6 in which R.sup.6 is C.sub.8-26 aliphatic hydrocarbon residue provided that at least one of R.sup.1 and R.sup.2 is --OCONHR.sup.6 ; and R.sup.3, R.sup.4 and R.sup.5 independently represent hydrogen or lower alkyl, or ##STR2## represents cyclic ammonio, exhibit inhibitory activity to multiplication of tumor cells and antimicrobial activity.

Phospholipid carbamates

New ethylene glycol derivatives, inclusive of salts thereof, which have the formula: ##STR1## wherein n is an integer of 1 to 15; R.sup.1 is an aliphatic hydrocarbon group containing 6 to 26 carbon atoms; R.sup.2, R.sup.3 and R.sup.4 are independently H or lower alkyl, or ##STR2## represents a cyclic ammonio group, exhibit inhibitory activity to multiplication of tumor cells and antimicrobial activity.

Ethylene glycol derivatives having anti-protozoan, anti-fungal and

Tridecyloxy- or tetradecyloxy-propane derivatives of the formula: ##STR1## wherein R.sup.1 is tridecyl or tetradecyl, R.sup.2 is hydrogen or --OCH.sub.3, and R.sup.3, R.sup.4 and R.sup.5 independently represent hydrogen or C.sub.1-3 alkyl, or ##STR2## represents cyclic ammonio, and their salts, have inhibitory activity to multiplication of tumor cells and antimicrobial activity.

Tridecyloxy- or tetradecyloxy-propane derivatives

Ethylene glycol derivatives, inclusive of salts thereof, which have the formula: ##STR1## wherein R.sup.1 is C.sub.8-26 aliphatic hydrocarbon residue; R.sup.2, R.sup.3 and R.sup.4 are each hydrogen or lower alkyl which may be substituted, or --N.sup.+ R.sup.2 R.sup.3 R.sup.4 represents cyclic ammonio, exhibit inhibitory activity to multiplication of tumor cells and antimicrobial activity.

Certain heterocyclic ammonio phosphate derivatives

Certain phosphoric acid ester derivatives of 1,3-dioxy propane

New carbamic acid esters, inclusive of salts thereof, which have the formula: ##STR1## wherein n is zero or 1; R.sup.1 and R.sup.2 independently represent --H, --OCH.sub.3 or --OCONHR.sup.6 ; in which R.sup.6 is C.sub.8-26 aliphatic hydrocarbon residue provided that at least one of R.sup.1 and R.sup.2 is --OCONHR.sup.6 ; and R.sup.3, R.sup.4 and R.sup.5 independently represent hydrogen or lower alkyl, or ##STR2## represents cyclic ammonio, exhibit inhibitory activity to multiplication of tumor cells and antimicrobial activity.

Growing community of inventors

Omiya, Japan

Motoo Hozumi