University of Alberta

Mostofa Hena

D Lorne Tyrrell

James Nieman

Appan Srinivas Kandadai

Alexandr Belovodskiy

Michael Houghton

Wen Fu

Jack Jhamandas

Ryoichi Kimura

Kamlesh Kumar Sahu

Michael A Joyce

Elena Arutyunova

Bing Bai

M Joanne Lemieux

The present disclosure provides compounds that are amylin receptor antagonist compounds, compositions that include the subject compounds, methods for preparing and using the amylin receptor antagonists, and compositions containing the amylin receptor antagonists for treating, preventing, or ameliorating Alzheimer's disease. Aspects of the present disclosure include a method of inhibiting activity of an amylin receptor by administering to a subject in need thereof a therapeutically effective amount of an amylin receptor antagonist.

Compounds for the treatment of Alzheimer's disease

The present disclosure provides compounds and methods for inhibiting a virus infection, such as a Baltimore Group IV RNA virus infection. Aspects of the present disclosure also include methods of treating a Baltimore Group IV RNA virus infection in a subject. The present disclosure also provides pharmaceutical compositions related to the same.

RNA virus inhibitor compounds and uses thereof

Growing community of inventors

Edmonton, Canada

Mostofa Hena