Imam Mohammad Ibn Saud Islamic University

Mostafa R Abukhadra

Hassan Ahmed Rudayni

Ahmed Aly Allam

Islam R Sayed

Aya Fadlallah Abdelmonem Mohamed

Nohan Nasser Abdelfattah Ahmed

A drug delivery system including a nanocomposite. The nanocomposite includes a zinc phosphate core, a hydroxyapatite shell, and chitosan. The hydroxyapatite shell at least partially encloses the zinc phosphate core. Further, the chitosan at least partially wraps around the hydroxyapatite shell. The chitosan interacts with the hydroxyapatite shell through hydrogen bonding, and the nanocomposite is loaded with oxaliplatin to form the drug delivery system.

Hydroxyapatite-enclosed zinc phosphate nanocomposite

A method of cytotoxically treating cancer with aluminum silicate nanorods (SNRs) including aluminum, iron, magnesium, oxygen, potassium, and oxygen comprises contacting the SNRs at a concentration of 0.5 to 2 μg/mL with a cancerous sample. The aluminum silicate nanorods have a longest dimension of 100 nanometers (nm) to 5500 nm and a diameter of 20 nm to 250 nm. The SNRs are porous with a pore size of 1 nm to 12 nm and include cisplatin in an amount of 20 to 300 mg/g. The cancerous sample has a reduced cell viability after the contacting.

Synthesis and characterization of glauconite-based silicate nanorods as anticancer agent

Chitosan-hybridized zinc phosphate/hydroxyapatite nanostructure-based drug delivery system

Growing community of inventors

Riyadh, Saudi Arabia

Mostafa R Abukhadra