University of California

Moses A Greenfield

Alain L Fymat

Wai-Nang P Lee

This invention comprises a method and apparatus for measuring both the absolute levels and variations of radioactivity emitted following administration of suitable radioisotopes during a test period by selected organs. Miniaturized radiation detectors for measuring two different types of radiation, such as gamma rays and photons, for example, are modified by the addition of mutual overlap coincidence units, scalers, single channel analyzers and time-gates. The individual detector units are appropriately arranged to form a probe or collar in either a strip or a checkerboard configuration, extending around the neck to study the thyroid gland or other gland organ to be analyzed. The associated electronic architecture is appropriately designed in either simplex or multiplex circuit patterns. Measurements are performed according to an established, preprogrammed time schedule that is reflective of the functional processes of the organ undergoing testing, and which separately determine the background radiation and that emanating from the organ or gland being examined. The data is recorded and processed by a dedicated microcomputer means. With a properly chosen radiopharmaceutical, the measurements provide specific data useful for clinical evaluation of the physiological functions and morphological features of the organ.

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Sherman Oaks, CA, United States of America

Moses A Greenfield