Sygnis Bioscience Gmbh & Co Kg

Biogen Idec, Inc.

Moritz Rossner

Klaus-Armin Nave

Rico Laage

Armin Schneider

Sylvia Grünewald

Sylvia Gruenewald

Rohini Kuner

Bernhard Götz

Markus Schwaninger

Stephanie Jomana Naim

Birgitta Kammandel

Annette Trutzel

Gisela Eisenhardt

Dieter Newrzella

Achim Fischer

Bettina Klaussner

Gerhard Vogt

C Linda Burkly

The invention relates to various methods of detecting and analyzing protein interactions in a cell, which methods involve the appearance of a specific protein interaction being converted to a permanent detection signal by means of providing, in a manner dependent on said protein interaction, a recombinase activity or protease activity.

Method for detecting and analyzing protein interactions in-vivo

Described are various methods of detecting and analyzing protein interactions in a cell. The specific protein interaction is detected by a permanent signal generated by a recombinase activity or protease activity that depends on the protein interaction.

Method for detecting and analyzing protein interactions in vivo

The present invention relates to a gene and the coded protein thereof that is involved in the development of sequelae of local ischaemia. The new protein is a serine threonine protein kinase and provides a new therapeutic approach to the prophylaxis and therapy of apoplexy.

Nucleic acid molecule encoding a neuronal serine-threonine protein kinase

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Goettingen, Germany

Moritz Rossner