The Yokohama Rubber Co., Ltd.

Hitachi, Ltd.

The Board of the Rubber Research Institute of Malaysia

Morihisa Machida

Kunio Kageyama

Shoichiro Ozaki

Seiichiro Ogawa

Yoshio Tajima

Takahiko Akiyama

Tatsuo Isahai

Daijiro Shiroki

Hideo Nakatsumi

Yoshitaka Udagawa

Naoto Takechi

Akihiro Isaka

Inositol compounds grouped into an aminocyclitol family are disclosed which have stereospecific structure and optical activity and find application to the manufacture of medicinal products and agricultural chemicals. The compound is produced with use of optically active L-quebrachitol as a starting material and by way of specific steps of reaction.

Optically active aminocyclitols

Optically active diols and hydroxycarboxylic acids and their esters are produced by deriving 1L-1,2:5,6-di-O-cyclohexylidene-chiro-inositol from 1L-chiro-inositol as an asymmetric source, followed by introduction of a selected class of sterically hindering and asymmetrically reactive groups into the first-mentioned compound and by subsequent reduction of the resulting compound. Seven specific inositols are also derivable from synthesis of those ultimate compounds.

Optically isomeric inositol and process for making optically active

A laminate comprising an inner layer containing an acid/base indicator and an outer layer containing no acid/base indicator, wherein the inner layer is capable of undergoing a color change upon its contact with an acid or an alkali.

Laminate having indicator function

A method of synthesizing D-myoinositol-1-phosphate from 1,2-(R.sup.1)-3-R.sup.2 -myoinositol compounds of the formula ##STR1## wherein R.sup.1 is a bridging type protective group bonded to two oxygen atoms at the 1- and 2-position, and R.sup.2 is a protective group coupled to the oxygen atom at the 3-position. D-Myoinositol-1-phosphate is useful as an intermediate for the production of inositol-1,4,5-triphosphate.

Synthesis of D-myoinositol-1-phosphate

Purified L-quebrachitol is recovered in increased quantities from rubber latex by dissolving concentrated solutions or pulverized solids of the serums in methyl alcohol under specified extraction conditions.

Method of recovering L-quebrachitol from rubber latex serums

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Kanagawa, Japan

Morihisa Machida