Dong-a St Co., Ltd.

Dong-a Pharm. Co., Ltd.

Dong-a Pharmaceutical Co., Ltd

Korea University Research and Business Foundation

Moon-Ho Son

Soon Hoe Kim

Mi-Kyung Kim

Moohi Yoo

Woo Young Kwak

Heung Jae Kim

Tae Hyun Yoon

Jong Pil Min

Chang Yell Shin

Song-Hyen Choi

Jae Young Lee

Ji Eun Lee

Hyun Wook Kim

Mi Hwa Lee

Yu Na Chae

Kyung Jin Park

Eun Kyoung Yang

Ji Myun Jang

Young Sun Kang

Jin Joo Cha

Jung Eun Kim

Hae-Sun Kim

Hadong Kim

Gook Jun Ahn

Dae Ryong Cha

The present invention relates to a composition for preventing or treating renal diseases. The composition of the present invention improves lipid metabolism, prevents histological damage including renal fibrosis, alleviates microalbuminuria, and maintains nephrons of renal glomeruli. Therefore, the composition is useful for treating renal diseases.

Composition containing a DPP-IV inhibitor for preventing or treating renal diseases

The present invention relates to a pharmaceutical composition for the prevention and treatment of diabetes or obesity comprising as active ingredients a compound which inhibits the activity of dipeptidyl peptidase-IV (DPP-IV), a pharmaceutically acceptable salt thereof, a hydrate thereof, or a solvate thereof, and one or more other antidiabetic or antiobesity agents. The pharmaceutical composition exhibits excellent glucose tolerance and may be useful in the prevention and treatment of diabetes, obesity, and the like by effectively inhibiting blood glucose levels and reducing fat mass.

Pharmaceutical composition for prevention and treatment of diabetes or obesity comprising a compound that inhibits activity of dipeptidyl peptidase-IV, and other antidiabetic or antiobesity agents as active ingredients

The present invention provides a novel heterocyclic compound containing a beta-amino group, a method for preparing the same, and a pharmaceutical composition comprising the same heterocyclic compound or a pharmaceutically acceptable salt thereof as an active ingredient. The heterocyclic compound of the present invention exhibits excellent DPP-IV inhibitory activity and bioavailability and therefore can be useful for the prophylaxis or treatment of DPP-IV-related diseases such as diabetes or obesity.

DPP-IV inhibitor including beta-amino group, preparation method thereof and pharmaceutical composition containing the same for preventing and treating diabetes or obesity

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Suwon-si, South Korea

Moon-Ho Son