George Mason University

Monique Van Hoek

Barney Bishop

Keith M Davies

Ezra Myung Chul Chung

Shravani Bobde

Stephanie Barksdale

Peptides are described herein, in particular peptides having antimicrobial properties, as are compositions, articles, and kits comprising such peptides, and methods for using the peptides.

Antimicrobial peptides and compositions, methods, articles and kits relating thereto

Provided is an engineered antimicrobial peptide. Also provided is a composition comprising an engineered antimicrobial peptide. Provided is a method of treating a subject in need thereof, comprising administering a therapeutically effective amount of a composition comprising an engineered antimicrobial peptide. Also provided is a method of producing an engineered antimicrobial peptide.

Antimicrobial peptides and related methods

Peptides having antimicrobial properties are described herein, as are compositions containing such peptides, and methods for using the peptides.

Antimicrobial peptides with wound healing activity

Materials and methods for making and using cationic anti-microbial peptides (CAMPs), and compositions containing such peptides.

Antimicrobial peptides and uses therefore

A cationic antimicrobial peptide (CAMP) conjugate is disclosed. The CAMP conjugate may be made by identifying a suitable carrier peptide; identifying a suitable antimicrobial agent; creating a conjugate by conjugating the peptide with the antimicrobial agent; and evaluating and refining the conjugate. The peptide may be short peptide based on the sequence of a CAMP, such as human &#x3b2;-defensin-3. The peptide can be directly connected to the antimicrobial agent or through a linker segment. The antimicrobial agent may be connected to the peptide or the linker segment through stable or cleavable bonding. The peptide may carry and facilitate the delivery of the conjugated antimicrobial agent to a microbe.

Growing community of inventors

Centreville, VA, United States of America

Monique Van Hoek