Sorin Group Italia S.r.l.

Corcym S.r.l.

Monica Francesca Achiluzzi

Felice Giuseppe Carlino

Paolo Gaschino

Giovanni Rolando

Laura Ghione

Giovanni Giordano

Andrea Marchisio

Xavier Ruyra Baliarda

Paolo Monelli

Marco Bussone

Francesco Valle

Silvano Moiso

Giovanni Righini

Massimiliano Ares

Antonella Orecchia

Felice Guiseppe Carlino

Disclosed herein is a deployment instrument including: a shaft () having a longitudinal axis (X); a handle () at a first end of the shaft (); and a carrier portion () at a second end of the shaft (). The carrier portion () is configured for holding an expandable heart valve prosthesis in a radially collapsed condition for delivery to the implantation site. The carrier portion () includes a hub () fixed to the handle () via the shaft (), a first deployment element () and a second deployment element (), each of said first deployment element () and second deployment element () configured to hold a corresponding portion of an expandable heart valve N prosthesis in a radially collapsed condition. A drive member () is provided which is configured to operate the first deployment element () and the second deployment element () in first and second opposite directions. The instrument is also provided with a mechanism to allow a displacement of the second deployment element in the second direction independently of the drive member ().

Device for the in-situ delivery of heart valve prosthesis

In certain embodiments, a multiple component heart valve prosthesis includes an abutment ring and a removable bioprosthetic heart valve. The abutment ring is configured for attachment at a heart valve annulus location and includes a locking system. The removable bioprosthetic heart valve includes a valve frame and at least one locking feature. The at least one locking feature is configured to be received by the locking system. The bioprosthetic heart valve can be rotated relative to the abutment ring such that the at least one locking feature transitions from a disengaged position to a first engaged position. When in the disengaged position the bioprosthetic heart valve may be removed from the abutment ring, and when rotated to the engaged position the bioprosthetic heart valve is restrained from axial movement relative to the abutment ring.

Two-part mitral valve and implant method

A bendable medical instrument including: a handle at a proximal end of the bendable medical instrument, a modular distal shaft including a plurality of vertebrae configured to bend and situated near a distal end of the bendable medical instrument, a bendable internal rod disposed through at least some of the plurality of vertebrae, the bendable internal rod having a modular cell structure, and a distal tip coupled to the modular distal shaft at the distal end. The plurality of vertebrae configured to bend to position the distal tip in a patient and the bendable internal rod configured to bend with the plurality of vertebrae.

Bendable cardiac surgery instruments

In certain embodiments, an implantation accessory for placement at a heart valve annulus location of a patients heart, the annulus having a first axis, the implantation accessory comprising: a first surface; a second axis perpendicular to the first surface; and, a maneuvering system for aligning the first axis and the second axis. In certain embodiments, a removable bioprosthetic heart valve assembly for implantation into an abutment ring attached at a heart valve annulus location of a patients heart, the abutment ring having a first axis, the removable bioprosthetic heart valve assembly includes a bioprosthetic valve for coupling to the abutment ring and a holder. The holder, detachably coupled to the bioprosthetic valve, includes a first surface, a second axis perpendicular to the first surface, and a maneuvering system for aligning the first axis and the second axis. Methods of implantation are also disclosed.

Tiltable tools for heart valve prosthesis

The disclosure relates to a holder () for a heart valve prosthesis () including a radially contractible armature () and a prosthetic valve carried by said armature (). The holder () includes an annular member () having a longitudinal axis (xl) and comprising a plurality of supporting formations (), said supporting formations () protruding radially inwardly of said annular member (), and a locking member () configured for coupling with said annular member (). Each supporting formation () includes a coupling profile or feature () configured for engaging the armature () of a heart valve prosthesis (). The coupling profile or feature () being configured to prevent the displacement of the armature () along said longitudinal axis and being configured to prevent rotation of the armature () around the longitudinal axis (X), while leaving the armature () unconstrained in a radially inward direction. The locking member () is configured to removably mate with the annular member () to provide a radial constraint to the armature in a radially inward direction at the supporting formations ().

Holder for heart valve prosthesis, a storage arrangement for a heart valve prosthesis, and a crimping kit and method

A cardiac valve prosthesis including an armature for anchorage of the valve prosthesis at an implantation site. The armature defining a lumen for the passage of the blood flow and having a longitudinal axis, and a set of prosthetic valve leaflets supported by said armature and configured to move, under the action of blood flow, in a radially divaricated condition to enable the flow of blood through said lumen in a first direction, and in a radially contracted condition, in which said valve leaflets co-operate with one another and block the flow of blood through the prosthesis in the direction opposite said first direction. The armature including an annular part and a pattern of arches struts carried by said annular part, said pattern of arched struts having proximal ends connected to said annular part, and distal ends spaced axially from the proximal ends and opposite said annular part, a plurality of sets of anchoring formations configured to protrude radially outwardly of said annular part, each set being supported by a least one of said annular part and a corresponding arched strut, and a plurality of support posts, each support post being supported by adjacent arched struts, wherein the sets of anchoring formations alternate with the support posts around said longitudinal axis.

Cardiac valve prosthesis

An implant device (V), such as a heart valve, for implantation in an animal body includes an annular structure and one or more elongated anchoring members deployable to a deployed condition for insertion into an animal body. The anchoring members are retractable from the deployed condition to a rolled up condition wherein the anchoring members protrude radially out from the annular structure of the device (V) to provide anchoring to a body structure (AS) of an animal. In the rolled up condition the anchoring members at least partly protrude axially of the annular structure of the device (V).

Implant device and implantation kit

Disclosed herein is a loading system () for implantable prostheses, specifically heart valve prostheses. The loading system () may be pre-mounted in a storage container (J) filled with a preservation solution with the prosthesis attached thereto, and may provide one or more deployment elements of a delivery instrument as receivers () for the loading of the prosthesis ().

Loading system for an implantable prosthesis and related loading method

A cardiac valve prosthesis including an armature for anchorage of the valve prosthesis at an implantation site. The armature defining a lumen for the passage of the blood flow and having a longitudinal axis, and a set of prosthetic valve leaflets supported by said armature and configured to move, under the action of blood flow, in a radially divaricated condition to enable the flow of blood through said lumen in a first direction, and in a radially contracted condition, in which said valve leaflets co-operate with one another and block the flow of blood through the prosthesis in the direction opposite said first direction. The armature including an annular part and a pattern of arched struts carried by said annular part, said pattern of arched struts having proximal ends connected to said annular part, and distal ends spaced axially from the proximal ends and opposite said annular part, a plurality of sets of anchoring formations configured to protrude radially outwardly of said annular part, each set being supported by at least one of said annular part and a corresponding arched strut, and a plurality of support posts, each support post being supported by adjacent arched struts, wherein the sets of anchoring formations alternate with the support posts around said longitudinal axis.

A heart valve prosthesis configured to be implanted at cardiac valve annulus located at an interface between a ventricle (LV) and an atrium (LA), the heart valve prosthesis including:

Heart valve prosthesis

A collapsible valve prosthesis includes an armature and a set of prosthetic valve leaflets supported by the armature. The armature is expandable from a contracted condition to an expanded condition for anchoring at an annulus of a natural valve site, and includes a tubular intra-annular portion defining a blood flow lumen having an inflow side and an outflow side. The tubular intra-annular portion supports the prosthetic valve leaflets in the blood flow lumen and is provided with outward formations for coupling with the natural valve site. The armature includes an over-annular portion linked to the intra-annular portion to extend collar-like over the annulus of the natural valve site at the inflow side of the blood flow lumen. The armature may also include an under-annular portion to extend collar-like at the outflow side of the blood flow lumen. The prosthesis may permit mitral valve replacement (MVR) without removing the native valve leaflets and the chordae tendineae.

Collapsible valve prosthesis

Described is a prosthetic device and methods for repairing a mitral valve having an annulus, leaflets, and chordae tendinae. The device comprises an elongate band including a plurality of reference elements that are located along the elongate band and protrude inwardly with respect thereto towards a center of the annulus, the plurality of reference elements being adapted to receive a corresponding plurality of artificial cords that are tied onto the reference elements and the plurality of reference elements adapted to be cut or removed in order to release the tied artificial cords.

Apparatus and method for chordal replacement

A support device for implanting stentless valve prostheses, such as biological heart valves, includes a hub and a plurality of support portions for supporting the stentless valve prosthesis. The hub defines a manipulation axis for the device and is flexibly connected to the support portions to allow displacing the manipulation axis for the device between the support portions.

Growing community of inventors

Chivasso, Italy

Monica Francesca Achiluzzi