University of North Carolina at Chapel Hill

Mona Jasmine R Ahonen

Mark H Schoenfisch

Haibao Jin

Lei Yang

Kaitlyn Rose Rouillard

Evan Scott Feura

Dakota J Suchyta

Sara Elizabeth Maloney

Several embodiments of NO releasing structures are disclosed. In some embodiments, the structures are covalently modified to store and release nitric oxide. Some embodiments pertain to methods of making and use of these structures. The covalently modified polymer structures may be tailored to release nitric oxide in a controlled manner and are useful for treatment of various medical conditions.

Nitric oxide-releasing antibacterial polymers and scaffolds fabricated therefrom and methods pertaining thereto

Large molecular weight alginates which are covalently modified to store and release nitric oxide, as well as methods of making and use thereof, are disclosed herein. The covalently modified alginates may be tailored to release nitric oxide in a controlled manner and are useful for eradication of both planktonic and biofilm-based bacteria.

Nitric oxide-releasing alginates as biodegradable antibacterial scaffolds and methods pertaining thereto

Growing community of inventors

Chapel Hill, NC, United States of America

Mona Jasmine R Ahonen