Siemens Healthcare Diagnostics Gmbh

Mohiudeen Azhar

Kalpesh Mehta

Ragavendar Ms

Sudipa Galgalkar

Ishita Chakraborty

Ragavendar Madrassethuraman

Ragavendar M S

Karan Mohan

An optical discrimination apparatus adapted for use in PCR testing and the like. The apparatus includes a multi-color light emitter to emit excitation light, a sample holder configured to hold dye-marked nucleic acid fragments in a PCR solution at a position configured to receive the excitation light along a first direction, light emission collection optics configured to collect scattered excitation light and light emission (fluorescent emission) from the sample holder along a second direction that is approximately orthogonal to the first direction, a spectrally-dispersive element configured to spectrally disperse scattered light and emission light, and a spectral detector configured to receive the separated emission light and excitation light on different photosites of the spectral detector. Systems and methods are provided, as are other aspects.

Optical discrimination apparatus and methods adapted to monitor reactions

A method, device and a system of determining a concentration of one or more analytes in a sample is disclosed. In one aspect of the invention, the method includes introducing the sample through a channel. The method further includes illuminating the sample with light having varying wavelengths. Additionally, the method includes obtaining an image of the illuminated sample at each of the wavelengths. Furthermore, the method includes analyzing the image to determine the concentration of the one or more analytes.

Method, device and system for determining the concentration of analytes in a sample

A method () and a system () for generating a chromatically modified image of one or more components on a microscopic slide () is disclosed. In one aspect of the invention, the method includes obtaining the image of the one or more components on the microscopic slide (). Additionally, the method () includes processing the image to identify the one or more components. The method () further includes segmenting at least one part of the one or more components identified from the image. Furthermore, the method () includes chromatically modifying the at least one part of the one or more components and generating a chromatically modified image of the one or more components.

Method and system for generating a chromatically modified image of components in a microscopic slide

A method and system for determining a concentration of one or more analytes in whole blood is provided. In one aspect of the invention, the system includes a channel configured to carry whole blood. The system further includes a light source configured to emit light on the channel. Additionally, the system includes an actuation module associable with the channel, wherein the actuation module is configured to generate a cell-free plasma layer in the channel. Furthermore, the system includes an optical module associable with the channel.

Method and device for determining the concentration of analytes in whole blood

A method and a device for determining a concentration of one or more analytes in a whole blood sample is disclosed. In one aspect of the invention, the method includes introducing the sample in a channel. The method further includes generating a cell-free plasma region in the channel, wherein the cell-free plasma region is generated in the channel based on rouleaux effect. The method further includes illuminating the sample with light having varying wavelengths. Additionally, the method includes obtaining an image of the illuminated sample at each of the wavelengths. Furthermore, the method includes analyzing the image to determine the concentration of the one or more analytes.

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Bengaluru, India

Mohiudeen Azhar