Jubilant Epicore LLC

Mohd Zainuddin

Subramanyam Janardhan Tantry

Mahanandeesha S Hallur

Purushottam Dewang

Kannan Murugan

Sreekala Nair

Chandru Gajendran

Sriram K Rajagopal

Sridharan Rajagopal

Chandrika Mulakala

Dhanalakshmi Sivanandhan

Pravin Iyer

Durga Prasanna Kumar C H

Durga Prasanna Kumar CH

The present disclosure describes novel compounds of the general Formula (I), their analogs, tautomeric forms, stereoisomers, polymorphs, hydrates, solvates, pharmaceutically acceptable salts, pharmaceutical compositions, metabolites, and prodrugs thereof. These compounds can inhibit both LSD and HDAC and are useful as therapeutic or ameliorating agent for diseases that are involved in cellular growth such as malignant tumors, schizophrenia, Alzheimer's disease, parkinson's disease and the like.

Cyclopropyl-amide compounds as dual LSD1/HDAC inhibitors

The present disclosure describes novel compounds of the general Formula (I), their analogs, tautomeric forms, stereoisomers, polymorphs, hydrates, solvates, pharmaceutically acceptable salts, pharmaceutical compositions, metabolites, and prodrugs thereof. These compounds can inhibit both LSD and HDAC and are useful as therpeautic or ameliorating agent for diseases that are involved in cellular growth such as malignant tumors, schizophrenia, Alzheimer's disease, parkinson's disease and the like. 

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Bengaluru, India

Mohd Zainuddin