Malaysian Palm Oil Board

Commonwealth Scientific and Industrial Research Organisation

Mohd Basri Wahid

Ravigadevi Sambanthamurthi

Yew Ai Tan

Kalyana Sundram P Manickam

Anthony J Sinskey

ChoKyun Rha

Nagendran Balasundram

Soon Sen Leow

Hjh Che Anishas Hj Che Idris

Mahinda Abeywardena

Sambandan Tg

Salmiah Ahmad

Kalyana Sundram

Hazimah Abu Hassan

Siti Nor Akmar Abdullah

Ahmad Parveez Ghulam Kadir

Hoong Seng Soi

T G Sambandan

Ooi Tian Lye

Tg Sambandan

Umi Salamah Ramli

Abdul Masani Mat Yunus

Sharifah Shahrul Rabiah Syed Alwee

Cheah Suan Choo

Samir Samman

Nihal S Agar

Dzulfazly Aminudin

Mohd Nurhisham Sattar

Nur Musyahadah Mazalan

Tuan Noor Mazne Tuan Ismail

Tan Sri Datuk Yusof Basiron

Abrizah Othman

Mohd Arif Abdul Manaf

Soon-Sen Leow

Omar Abdul Rasid

Leow Soon Sen Sen

T J Sambandan

J Sinskey Anthony

Tan Yew Ai Ai

A composition comprising extracts containing oil palm phenolics in an amount effective for use in a method of reducing cholesterol biosynthesis and thus preventing obesity. The composition up regulates fatty acid beta oxidation and down regulates cholesterol biosynthesis in livers. The composition is useful for prevention of obesity associated diseases. The composition delays the onset of obesity and attenuates the inflammatory response of atherogenic diet, whereby the composition aids to suppress the inflammatory response thereby ameliorating artherosclerosis. The composition delays weight gain or obesity thereby preventing the effects of dyslipidemia.

Anti-obesity and anti-dyslipidemic effects of oil palm phenolics in treating atherosclerosis and cardiovascular disease

A composition comprising caffeoylshikimic acids, protocatechuic acid, hydroxytyrosol, hydroxybenzoic acid, said caffeoylshikimic acids and their derivatives extracted from any part of oil palm including but not confined to the vegetation liquor of palm oil milling and palm oil mill effluent, and a method for use in the preparation of a composition containing caffeoylshikimic acids, protocatechuic acid, hydroxytyrosol, hydroxybenzoic acid, said caffeoylshikimic acids and their derivatives. The method includes the steps of pre-concentrating an extract containing the caffeoylshikimic acids, protocatechuic acid, hydroxytyrosol, hydroxybenzoic acid, caffeoylshikimic acids and their derivatives and isolating the caffeoylshikimic acids, protocatechuic acid, hydroxytyrosol, hydroxybenzoic acid, said caffeoylshikimic acids and their derivatives from said extract by liquid chromatography, wherein the elution activity of said caffeoylshikimic acids, protocatechuic acid, hydroxytyrosol, hydroxybenzoic acid, with the caffeoylshikimic acids and their derivatives varying depending on the stationary phase and the composition of the mobile phase.

Composition comprising caffeoylshikimic acids, protocatechuic acid, hydroxytyrosol, hydroxybenzoic acid and their derivatives and method of preparation thereof

The present invention provides compositions and method for production of shikimic acid based on extracts obtained from oil palm-based materials, and more particularly oil palm-based waste materials and by-products. The method includes purifying shikimic acid from extracts comprising oil palm phenolics (OPP).

Compositions comprising shikimic acid obtained from oil palm-based materials

A composition comprising caffeoylshikimic acids, protocatechuic acid, hydroxytyrosol, hydroxybenzoic acid, caffeoylshikimic acids and their derivatives extracted from any part of oil palm including but not confined to the vegetation liquor of palm oil milling and palm oil mill effluent, and a method for use in the preparation of a composition containing caffeoylshikimic acids, protocatechuic acid, hydroxytyrosol, hydroxybenzoic acid, caffeoylshikimic acids and their derivatives. The method includes the steps of pre-concentrating an extract containing the caffeoylshikimic acids, protocatechuic acid, hydroxytyrosol, hydroxybenzoic acid, caffeoylshikimic acids and their derivatives and isolating said caffeoylshikimic acids, protocatechuic acid, hydroxytyrosol, hydroxybenzoic acid, caffeoylshikimic acids and their derivatives from said extract by liquid chromatography, wherein the elution activity of said caffeoylshikimic acids, protocatechuic acid, hydroxytyrosol, hydroxybenzoic acid, caffeoylshikimic acids and their derivatives vary depending on the stationary phase and the composition of the mobile phase.

The present invention provides compositions and method for production of shikimic acid based on extracts obtained from oil palm-based materials, and more particularly oil palm based waste materials and by-products. The method includes purifying shikimic acid from extracts comprising oil palm phenolics (OPP).

Compositions comprising shikimic acid obtained from oil palm based materials and method of producing thereof

The invention provides a composition the prevention and treatment of cardiovascular disease, wherein said composition compounds obtained from palm oil mill effluents, in particular from vegetative liquor from the milling of palm oil fruit.

Composition for use in the prevention and treatment of cardiovascular diseases

The present invention relates to a composition for the use in improving vascular health, including treating and preventing vascular diseases and diseases related thereto, using a botanical extract of oil palm vegetation liquor from the palm oil milling process.

Composition and method for improving vascular health

The invention provides a composition for the prevention and inhibition of oxidative stress and hemolysis in human red blood cell wherein said composition compounds obtained from the aqueous stream of palm oil milling (palm oil vegetation liquor), in particular from vegetative liquor from the milling of palm oil fruit.

Botanical extract from the aqueous stream of the palm oil milling process for the prevention and inhibition of oxidative stress and haemolysis in human red blood cells

The present invention relates to a composition comprising oil palm phenolics for use in providing neuroprotective effects and improving cognitive and motor functions abilities.

Composition comprising oil palm phenolics for use in providing neuroprotective effects and cognitive-enhancement

A cosmeceutical composition comprising phenolic compounds, fruit acids and sugars, extracted from the vegetation liquor of the palm oil milling process has been suggested. This composition is rich in antioxidants, and significantly improves skin health, including preventing aging of skin.

Botanical extracts from oil palm vegetation liquor for cosmeceutical applications

A process for preparing palm-based polyol monomer includes reacting unsaturated fatty acids or its corresponding triglycerides with polyhydric alcohol. In particular, one example uses oleic acid with about 70% purity as the starting material for preparing the polyol monomer. Moreover, another example uses refined, bleached, and deodorized (RBD) palm olein as an alternative to oleic acid as the starting material. The preparation of the polyol monomer involves the production of monoglyceride of unsaturated fatty acids, which was further epoxidized with peracid and finally ring opened with polyhydric alcohols. Such polyol monomer is used as a raw material for the production of various types of polyurethane products.

Process for the production of a polyol monomer

The present invention relates to an isolated nucleic acid molecule comprising a sequence of nucleotides encoding a &#x3b2;-ketoacyl ACP synthase II from a plant, or a variant, derivative, homolog or analog of said &#x3b2;-ketoacyl ACP synthase II. The invention also relates to an isolated &#x3b2;-ketoacyl ACP synthase II enzyme from a plant. The polynucleotide sequences of the present invention may be used inter alia for the generation of cells or plants comprising such cells which have a modified phenotype and/or which exhibit a desired characteristic.

Recombinant enzyme and uses therefor

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Selangor Darul Ehsan, Malaysia

Mohd Basri Wahid