Other

Isp Investments Inc.

Sartre Satire LLC

Mohammed Abdul Rahman

Chris Tsu

Feng Han

Andy P Annadurai

Andrew Xian Chen

Hailiang Chen

Thomas Durig

Majid Keshtmand

Yunxia Bi

James David Lester

Randy Bull

James Cecil Free

Sally A Look

A stable and high loading ternary solid dispersion composition comprising (a) about 50% wt. to about 90% wt. of amorphous Efavirenz; (b) about 10% wt. to about 50% wt. of polyvinyl pyrrolidone (PVP), a first polymer; (c) about 1% wt. to about 30% wt. of a water-soluble second polymer; and (d) optionally about 0.1% wt. to about 50% wt. of at least one pharmaceutically acceptable excipient. Also discloses a high loading ternary composition comprising (a) a solid dispersion composition comprising (i) about 50% wt. to about 90% wt. of amorphous Efavirenz; (ii) about 10% wt. to about 50% wt. of polyvinyl pyrrolidone, a first polymer; (b) about 1% wt. to about 30% wt. of a water-soluble second polymer blended with solid dispersion of composition of (a); and (c) optionally about 0.1% wt. to about 50% wt. of at least one pharmaceutically acceptable excipient. Additionally discloses a method for preparing solid dosage forms comprising (i) amorphous Efavirenz and (ii) polyvinyl pyrrolidone (PVP), a first polymer; (iii) a water-soluble second polymer; and (iv) optionally, at least one pharmaceutical excipients.

Highly loaded amorphous efavirenz composition and process for preparing the same

Provided are methods for reducing the excipient load of pharmaceutical formulations containing 3-fluoro-7-(2,2,2-trifluoroethoxy)phenoxathiin 10,10-dioxide as the active pharmaceutical ingredient, and compositions related thereto. In particular, provided is a pharmaceutical product comprising 3-fluoro-7-(2,2,2-trifluoroethoxy)phenoxathiin 10,10-dioxide and a stabilizer admixed throughout a solid-form unilamellar matrix, wherein the ratio of 3-fluoro-7-(2,2,2-trifluoroethoxy)phenoxathiin 10,10-dioxide to stabilizer ranges from about 2:3 to about 1:10, and related methods of forming the pharmaceutical product.

Oral antidepressant formulation with reduced excipient load

Method and apparatus for processing data packets within a communication system such as a synchronous optical network (SONET) detect an invalid byte and drop and shift bytes of data to address an invalid byte. A method according to one embodiment of the present invention, includes receiving a first data packet in the communication system. Thereafter, it is determined whether this packet ends with both a valid byte and an invalid byte of data. If both the valid and invalid bytes are present, the invalid byte is dropped and a valid byte from a succeeding data packet is concatenated with the valid byte of the first data packet, and byte shifting occurs in the succeeding data packet. Byte shifting continues until a second packet ending with an invalid byte is encountered. Skipping a clock cycle at the end of the second packet with the invalid byte results in packets with only valid data.

Circuit and method for processing communication packets and valid data bytes

Method and circuitry for de-skewing data in data communication networks such as a SONET. The data is sent from a system chip to a framer chip where the data is de-skewed. To detect data skew, the system chip sends a training sequence to the framer chip. The information bits sent to the framer chip are searched in order to detect the training sequence. The training sequences contain clear transition patterns at which all 16 bits of the transmit data and the TCTL signal line are inverted. If any bit does not invert, this bit must be a skewed bit. Based on the data one clock cycle before and one clock cycle after this transition, the skewed bit can be corrected back. After the data skew is detected, a multiplexing logic circuitry is used to correct the skew based on one clock cycle either before or after the transition. The multiplexing logic circuitry includes at least three registers coupled to the inputs of the multiplexing logic circuitry.

Method and circuit for de-skewing data in a communication system

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Columbia, MD, United States of America

Mohammed Abdul Rahman