University of Michigan

Mohammad Reza Abidian

David C Martin

Daryl R Kipke

Paul S Cederna

Sarah M Richardson-Burns

Jeffrey L Hendricks

Melanie G Urbanchek

Brent M Egeland

Antonio Peramo

Eugene D Daneshvar

Laura Povlich

Kim Donghwan

A hybrid bioelectrical interface (HBI) device can be an implantable device comprising an abiotic component operable to transmit charge via electrons or ions; a biological component interfacing with the neural tissue, the biological component being sourced from biologic, biologically-derived, or bio-functionalized material; and a conjugated polymer component that together provide a way to chronically interface living neural tissue with electronic devices for extended durations (e.g. greater than 10 years). In some embodiments, conjugated polymers provide a functional electrical interface for charge transfer and signal transduction between the nervous system and an electronic device (e.g. robotic prosthetic limb, retinal implant, microchip).

Hybrid bioelectrical interface device

Drug delivery devices, their manufacture, and their use comprising electrocontractile nanotubes that can be used for precise controlled bioactive substance release for example, medical, veterinary, pharmaceutical compounds and growth factors. The conducting polymer nanotubes significantly decrease the impedance and increase the charge capacity of recording electrode sites on microfabricated electrode devices. Bioactive substances released from the nanotubes can be controlled in a desired fashion by controlled electrical stimulation of the nanotubes.

Conducting polymer nanotube actuators for precisely controlled release of medicine and bioactive molecules

Growing community of inventors

State College, PA, United States of America

Mohammad Reza Abidian