Wayne State University

Mohammad Mehrmohammadi

Sonia S Hassan

Edgar Hernandez-Andrade

Yan Yan

Nardhy Gomez-Lopez

Maryam Basij

Ivan Avrutsky

Juri G Gelovani

A photoacoustic tomography system includes a first ring-shaped mirror having a central axis therethrough and configured to converge light inwardly towards the central axis and a subject, and an adjustment mechanism configured to move the first ring-shaped mirror along the central axis to a plurality of different positions. Each position of the plurality of different positions allows the first ring-shaped mirror to illuminate a respective ring of light around a respective portion of the subject, and an acoustic signal detector is movable along the central axis such that acoustic signals can be detected from the respective portion of the subject when illuminated by the first ring-shaped mirror while at each respective position of the plurality of different positions.

Omnidirectional photoacoustic tomography system

Methods and system are described for multi-modal, multi-parametric, non-invasive, and real-time assessment of cervical tissue through a multi-modal probe device for use within a vaginal canal and an associated imaging system to assess a risk of preterm delivery of an expectant mother. The multi-modal system may include ultrasound (US) imaging, viscoelastic (VE) imaging, and/or photoacoustic (PA) imaging of the cervical issue to determine cervical biomarker information indicative of parameters including, but not limited to, a collagen to water ratio such that a more water dominant ratio is indicative of a risk of preterm delivery.

Ultrasound, photoacoustic, and viscoelastic imaging systems and methods for cervical analysis to assess risk of preterm delivery

Methods and system are described for multi-parametric, non-invasive, and real-time assessment of blood perfusion and oxygenation in the fetal brain during labor and delivery of a fetus through a vaginal birth canal of a maternal pelvis, and include positioning a probe device in the maternal pelvis during active labor, transmitting and receiving a plurality of ultrasound (US) and photoacoustic (PA) signals between the probe device and fetal brain, displaying in real-time on an US machine communicatively coupled to the probe device one or more images of venous and arterial blood flow of respective blood vessels in the fetal brain, measuring oxygen saturation of the respective venous and arterial blood vessels based on data from the one or more images, and estimating the oxygen measurement in the fetal brain during active labor based on the measured oxygen saturation.

Ultrasound and photoacoustic systems and methods for fetal brain assessment during delivery

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Farmington Hills, MI, United States of America

Mohammad Mehrmohammadi