Graphene-dx, Inc.

General Electric Company

Northeastern University

Rite Taste, LLC

Nano Lc-12, LLC

Other

Mohammad Esmaail Taslim

Edward Alvin Greenfield

Reza Mollaaghababa

Mehdi Abedi

Mohammed Fotouhi

Bahram Fotouhi

Kashayar Javaherian

Namal Nawana

Zahra Borzooeian

Thomas Olsen

Dylan Thorp

Liam Byers

Mitchell Noah

Evan Weiner

Robert Francis Manning

Daniel Edward Demers

Yiannis A Levendis

Thomas Edward Demarche

Robert Barry Solda

Samuel D Spring

Lalit K Parekh

Mohammad Fotouhi

Kashayar Java-Herian

A processing and detection system for detecting presence of at least one gluten protein in a food sample comprises a food processor including: a reservoir containing a process liquid for processing the food sample; a body that comprises a chamber configured to receive the food sample; and a pressing surface configured to press on the reservoir to cause the process liquid to exit the reservoir and mix with the food sample, thereby generating a processed food liquid; and an exit port configured to conduct the processed food liquid out of the food processor; and a cartridge including: at least one sensor configured to receive the processed food liquid and to generate an electrical signal in response to interaction with the at least one gluten protein in the processed food liquid, and an analyzer in electrical communication with the at least one sensor for detecting the electrical signal and determining the presence of the at least one gluten protein in the food sample based on the detected electrical signal.

Device and method for chemical analysis

In one aspect, a method of detecting tetrahydrocannabinol (THC) in a sample is disclosed, which comprises bringing the sample into contact with a graphene layer functionalized with an antibody exhibiting specific binding to THC, applying a time-varying electric field to said antibody-functionalized graphene layer, monitoring electrical resistance of said graphene layer in response to interaction with said sample, and detecting presence of THC in the sample by detecting a change in said electrical resistance indicative of interaction of THC with said anti-body functionalized graphene layer.

Methods and devices for detection of THC

Some embodiments provide methods and systems for creating ladder/standards as quality control tools for length-based separation of carbon nanotubes; determining the length purity; or measuring distribution of lengths of a collection of carbon nanotubes. Some embodiments further provide methods and systems for dispersing carbon nanotubes by conjugation of the carbon nanotubes with biomolecule moieties, specifically proteins. Further, some embodiments provide an indicator for length-based separation of carbon nanotubes via conjugation of one or more biomolecules onto the surfaces of the nanotubes. In some embodiments, such a method can include conjugating a biomolecule to the carbon nanotubes and subjecting the conjugated carbon nanotubes to silver-stained gel electrophoresis to separate the conjugated carbon nanotubes based on their lengths.

Length-based carbon nanotube ladders

Methods and devices for detecting a target agent of interest, e.g., a pathogen, in a sample are described herein. In some embodiments, a sensor is provided that can include a substrate, a graphene layer disposed on a surface of said substrate, and a protein bound to said graphene layer. The protein can be capable of binding to one or more target agents of interest, e.g., pathogens, etc. The binding of the protein to the one or more target agents of interest can generate a change in an electrical property of the graphene layer.

Disclosed are methods for separating carbon nanotubes on the basis of a specified parameter, such as length. The methods include labelling of the carbon nanotubes with a biological moiety, followed by SDS-PAGE and staining, to separate the carbon nanotubes on the basis of length and/or characterize their length. In some embodiments, egg-white lysozyme, conjugated covalently onto single-walled carbon nanotubes surfaces using carbodiimide method, followed by SDS-PAGE and visualization of the single-walled nanotubes using silver staining, provides high resolution characterization of length of the single-walled carbon nanotubes. This high precision, inexpensive, rapid and simple separation method obviates the need for centrifugation, additional chemical analyses, and expensive spectroscopic techniques such as Raman spectroscopy to visualize carbon nanotube bands. The disclosed methods find utility in quality-control in the manufacture of carbon nanotubes of specific lengths.

Length-based separation of carbon nanotubes

In one aspect, a method of detecting a pathogen, e.g.,bacterium,bacteria, gonorrhea bacteria and/or HPV, in a sample is disclosed, which comprises bringing a sample into contact with a graphene layer functionalized with an antibody exhibiting specific binding to the pathogen, monitoring electrical resistance of said antibody-functionalized graphene layer in response to interaction with said sample, and detecting presence of the pathogen in said sample by detecting a change in said electrical resistance indicative of interaction of the pathogen with said antibody-functionalized graphene layer. For example, a decrease of the electrical resistance of the graphene layer can indicate the presence of the pathogen in the sample under study. In some embodiments, a method according to the present teachings is capable of detecting pathogens, such asbacteria,bacteria, gonorrhea bacteria and HPV in a sample at a concentration as low as 4 cfu per 100 grams of a sample.

Methods and devices for detection of pathogens

In one aspect, the present invention is generally directed to methods for measuring distribution of lengths of a collection of carbon nanotubes. In particular, the present teachings provide an indicator for length-based separation of carbon nanotubes (CNTs) via conjugation of one or more biomolecules onto the surfaces of the nanotubes. As discussed in more detail below, in some embodiments, such a method can include conjugating a biomolecule to the carbon nanotubes and subject the conjugated carbon nanotubes to silver-stained gel electrophoresis to separate the conjugated carbon nanotubes based on their lengths.

In an embodiment of the invention, a non-rotating wind energy generator uses the fluid flow principles of vortex shedding and transverse galloping to generate oscillatory motion of a beam, and alternators, optionally located near both ends of the beam, generate electrical power when the beam is in motion.

Non-rotating wind energy generator

In an embodiment of the invention, a non-rotating wind energy generator uses the fluid flow principles of vortex shedding and transverse galloping to generate oscillatory, linear motion of a beam, and linear alternators, optionally located near both ends of the beam, generate electrical power when the beam is in motion.

A turbine airfoil includes pressure and suction sidewalls joined together at opposite leading and trailing edges, and at a forward bridge spaced behind the leading edge to define a flow channel. The bridge includes a row of impingement holes. The flow channel includes a row of fins behind the leading edge, a row of first turbulators behind the pressure sidewall, and row of second turbulators behind the suction sidewall. The fins and turbulators have different configurations for increasing internal surface area and heat transfer for back side cooling the leading edge by the cooling air.

Castellated turbine airfoil

A turbine engine airfoil includes a three-pass serpentine shaped cooling cavity including a leading edge chamber, an oversized intermediate chamber, and a trailing edge chamber in flow communication. The cavity further includes a combination of a plurality of ribs and a plurality of pins, a purge air swirler, a turning vane, and a metering partition which mixes the high pressure air and provides increased air cooling and uniform flow control in the airfoil. The metering partition provides a decrease of the air pressure in the trailing edge chamber allowing for an increase in the number of trailing edge slots.

Turbine airfoil and methods for airfoil cooling

An improved cooling passage configuration for a gas turbine engine airfoil is disclosed for enhancing convective cooling over that afforded by conventional wall turbulator ribs. An internal cooling passage bounded by pressure and suction side walls and at least one partition has raised turbulator ribs disposed on at least one side wall and the partition. A side wall turbulator rib extends over at least a portion of the side wall and abuts the partition. A turbulator rib disposed on the partition extends from a point spaced from the wall rib to the opposed side wall. The gap formed between the partition rib and wall rib accelerates a coolant flow passing therethrough, locally enhancing convective heat transfer. Partition ribs may be aligned with or offset from the wall ribs in the spanwise direction and may be normal to the primary direction of cooling flow or angled thereto. Convective heat transfer is particularly enhanced in flow passages having cavity height blockage due to wall ribs greater than about 10%.

Growing community of inventors

Needham, MA, United States of America

Mohammad Esmaail Taslim