Electro-cat, LLC

3dt Holdings, LLC

Mohamed Reza Movahed

Ghassan S Kassab

Hans Gregersen

Devices and systems to measure luminal organ parameters using impedance. In at least one embodiment of an impedance device of the present disclosure, the impedance device comprises an elongated body having a distal body end and a pair of detection electrodes positioned in between a pair of excitation electrodes located at or near the distal body end, the pair of detection electrodes configured to obtain one or more conductance values within a mammalian luminal organ within a field generated by the pair of excitation electrodes, wherein a measured parameter of the mammalian luminal organ can be calculated based in part upon the one or more conductance values obtained by the device and a known distance between the pair of detection electrodes.

Devices and systems to measure luminal organ parameters using impedance

Methods for measuring cross-sectional areas in luminal organs. In at least one embodiment of a method for measuring a size parameter of a targeted treatment site of the present disclosure, the method comprises the steps of introducing an impedance device into a treatment site, the impedance device selected from the group consisting of an impedance catheter and an impedance wire; injecting a first solution of a first compound having a first conductivity into the treatment site; measuring a first conductance value at the treatment site using the impedance device, the first conductance value indicative of a bolus of the first solution, and calculating a size parameter of the treatment site based in part upon the first conductivity of the first solution, the first conductance.

Methods for measuring cross-sectional areas in luminal organs

The invention comprises a system, catheter and method for measuring the cross-sectional areas and pressure gradients in any hollow organ, such as, for example, blood vessels. One embodiment of such a system includes: an impedance catheter capable of being introduced into a targeted site; a solution delivery source; a constant current source; a balloon inflation control device; and a data acquisition and processing system that receives conductance and/or pressure gradient data from the catheter and calculates the cross-sectional area of the targeted site. In one embodiment, the catheter has an inflatable balloon along its longitudinal axis, thereby enabling the breakup of any materials causing stenosis at the targeted site and/or distention and delivery of an optional stent into the targeted site.

System and method for measuring cross-sectional areas and pressure gradients in luminal organs

The present disclosure comprises a system, catheter and method for measuring the cross-sectional areas and pressure gradients in any hollow organ, such as, for example, blood vessels. One embodiment of such a method includes the steps of introducing an impedance catheter into a treatment site, providing electrical current flow to the treatment site, injecting a first solution and measuring a first conductance value, injecting a second solution and measuring a second conductance value, and calculating the cross-sectional area of the treatment site, in part, based on the first and second conductance values.

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Irvine, CA, United States of America

Mohamed Reza Movahed