Qlt Phototherapeutics, Inc.

The University of British Columbia

Quadra Logic Technologies, Inc.

Novartis Ag

Qlt Inc.

Modestus O Obochi

Julia G Levy

Anna M Richter

David W Hunt

Guillermo O Simkin

Agnes How-Ching Chan

William C Stewart

Claude Aa Hariton

Green porphyrins act as antigen-specific immunomodulators in the active phase of an immune response to a particular antigen. This effect occurs at ambient light levels.

Green porphyrins as immunomodulators

Green porphyrins act as antigen-specific immunomodulators in the active phase of an immune response to a particular antigen, as well as to interfere with intercellular communication. These effects occur in the absence of radiation absorbed by the green porphyrin.

Donor tissue containing antigen-presenting cells (APCs) can be modified to reduce rejection when the donor tissue is used as an allograft by exposing the donor tissue which has been treated with a photosensitizing agent having an absorption maximum between 400-900 nm to a wavelength absorbed by the photosensitizing agent so as to attenuate the APCs in the donor tissue but wherein the light is not cytotoxic to the APCs.

Method to prevent transplant rejection

Growing community of inventors

Vancouver, Canada

Modestus O Obochi