Medical and Pharmaceutical Industry Technology and Development Center

Pharmaceutical Industry Technology and Development Center

Oneness Biotech Co.

Mo-Chi Cheng

Feng-Nien Ko

Chien-Jen Shih

Je-Yie Lin

Pey-Chyi Wu

Cheng-Ko Liu

Jen-Wei Chen

Fen Chen

Chao-Chi Yei

Tian-Shung Wu

Wei-Luen Chang

Wei-luen Chang

Disclosed is a method for wound healing comprising administering a subject in need thereof a therapeutically effective amount of a flavonoid compound, wherein the compound is preferably nonglycosylated flavone. Specifically, the present invention can be used for treating skin symptoms of a trauma, a burn, a scald and a chronic wound, and can be particularly used for healing a wound of a diabetes patient.

Use of flavonoids in manufacturing compositions for wound healing

A new use of a potent product extracted from rhizomes ofin treating a disease associated withsuch as gastritis, gastric ulcer or duodenal ulcer in a patient. The potent product is prepared by a process including the steps of a) preparing a crude extract from rhizomes of, said crude extract comprising 6-gingerol and 6-shogaol; b) introducing the crude extract to a normal phase chromatography column, and eluting the column with a first eluent having a polarity lower than that of a mixture of n-hexane and ethyl acetate in a weight ratio of 6:4 to obtain a potent fraction. Preferably, the potent fraction is substantially free of both 6-gingerol and 6-shogaol.

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The present invention discloses a new use of a potent product extracted from rhizomes ofin treating a disease associated withsuch as gastritis, gastric ulcer or duodenal ulcer in a patient. The potent product is prepared by a process including the steps of a) preparing a crude extract from rhizomes of, said crude extract comprising 6-gingerol and 6-shogaol; b) introducing the crude extract to a reverse phase chromatography column, and eluting the column with a first eluent having a polarity lower than water to obtain a first potent fraction or a second eluent having a polarity lower than that of the first eluent to obtain a second potent fraction. Preferably, the second potent fraction is substantially free of both 6-gingerol and 6-shogaol.

A polygalatenoside useful as an antidepressant agent having the formula is disclosed: wherein R, R' and R&#x2033; independently are H or R, provided that R, R&#x2032; and R&#x2033; are not all H, wherein Ris wherein Ris hydrogen, C1-C6 alkyl, C1-C6 alkoxy or halogen; or a pharmaceutically acceptable salt thereof. Preferably, Ris H.

Polygalatenosides and use thereof as an antidepressant agent

The invention discloses a pharmaceutical composition for preventing and/or treating peptic ulcer, including American ginseng or the extract thereof, and a method for preparing American ginseng extract, said method including extracting American ginseng with water or ethanol aqueous solution, and then ultrafiltrating, dialyzing, precipitating with ethanol, or performing reverse phase chromatography to obtain various fractions of extract with anti-peptic ulcer effect.

Anti-ulcer pharmaceutical composition and the preparation thereof

The invention discloses a pharmaceutical composition for preventing and/or treating peptic ulcer, includingor the extract thereof, and a method for preparingextract, said method including extractingwith water or ethanol aqueous solution, and then ultrafiltrating, dialyzing, precipitating with ethanol, or performing reverse phase chromatography to obtain various fractions of extract with anti-peptic ulcer effect.

Growing community of inventors

Taipei, Taiwan

Mo-Chi Cheng