Kaneka Corporation

Mitsutoshi Moro

Yasuyoshi Ueda

Takahiro Ueda

Shiro Kitamura

Tadao Ono

The present invention provides a stabilization method, a preservation method and the like method of reduced coenzyme Q, which is useful as functional nutritive foods, specific health foods and the like. Furthermore, the present invention provides a method for efficiently obtaining reduced coenzyme Qof high quality and by a method suitable for a commercial production. It is possible to handle and stably preserve reduced coenzyme Qunder a condition that oxidation by a molecular oxygen is inhibited by contacting reduced coenzyme Qwith, an ascorbic acid and citric acid or a related compound thereof, and thus a stabilized composition is obtained. Moreover, reduced coenzyme Qis converted into a crystalline state in such a condition that the formation of oxidized coenzyme Qas a byproduct is minimized by crystallizing reduced coenzyme Qin the presence of ascorbic acid or a related compound thereof etc., and thus a reduced coenzyme Qcrystal of high quality is produced. Furthermore, by successively crystallizing the generated reduced coenzyme Qin the presence of ascorbic acid or related compound thereof after reducing oxidized coenzyme Qto reduced coenzyme Qusing ascorbic acid or a related compound thereof, operations are simplified and minimized, and thus reduced coenzyme Qof high quality is produced.

[object Object]

The present invention provides a stabilization method, a preservation method and the like method of reduced coenzyme Q, which is useful as functional nutritive foods, specific health foods and the like. Furthermore, the present invention provides a method for efficiently obtaining reduced coenzyme Qof high quality and by a method suitable for a commercial production. It is possible to handle and stably preserve reduced coenzyme Qunder a condition that oxidation by a molecular oxygen is inhibited by contacting reduced coenzyme Qwith an ascorbic acid and citric acid or a related compound thereof, and thus a stabilized composition is obtained. Moreover, reduced coenzyme Qis converted into a crystalline state in such a condition that the formation of oxidized coenzyme Qas a byproduct is minimized by crystallizing reduced coenzyme Qin the presence of ascorbic acid or a related compound thereof, etc., and thus a reduced coenzyme Qcrystal of high quality is produced. Furthermore, by successively crystallizing the generated reduced coenzyme Q, in the presence of ascorbic acid or related compound thereof after reducing oxidized coenzyme Qto reduced coenzyme Qusing ascorbic acid or a related compound thereof, operations are simplified and minimized, and thus reduced coenzyme Qof high quality is produced.

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Takasago, Japan

Mitsutoshi Moro