Johnson and Johnson Vision Care, Inc.

Toray Industries, Inc.

Siemens Aktiengesellschaft

Mitsuru Yokota

Kazuhiko Fujisawa

Masataka Nakamura

Naoki Shimoyama

Douglas G Vanderlaan

Tsutomu Goshima

Tadahiro Uemura

Shuji Fujioka

Tobias Tyroller

Hideki Kenjo

Hiroya Koyama

Nobuo Saito

Takehiro Kohara

Kimihiro Kamasaka

Shinya Kiguchi

Satoshi Umeda

Kazushige Komaki

Yukie Morikawa

In one aspect, the invention relates to hydrolysis-resistant silicone compounds. In particular, disclosed are sterically hindered hydrolysis-resistant silicone compounds and improved purity hydrolysis-resistant silicone compounds. Also disclosed are processes for making hydrolysis-resistant silicone compounds; the products of the disclosed processes; compositions and polymers comprising the disclosed compounds and products of the disclosed processes; and ophthalmic lenses, for example contact lenses, intraocular lenses, artificial cornea, and spectacle lenses, comprising the disclosed compositions, disclosed polymers, disclosed compounds, and products of the disclosed processes. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.

Hydrolysis-resistant silicone compounds

Process for producing hydrolysis-resistant silicone compounds

In one aspect, the invention relates to silicone prepolymer compositions comprising a silicone prepolymer and a solvent. A soluble silicone prepolymer can be provided having increased average silicon content, thereby attaining a desired oxygen permeability. A solvent can be provided with a desired balance between hydrophilicity and hydrophobicity by selection and modification of the solvent molecular structure, resulting in molded polymer films and articles that exhibit minimal or nonexistent eye irritation and exhibit highly transparent products. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.

Silicone prepolymer solutions

In one aspect, the invention relates to methods of synthesizing acryloyl compounds, comprising the step of hydrosilylating a compound having the structure: with a compound having the structure A-H, wherein A comprises a siloxanyl group, to yield a compound having the structure: Compounds and compositions produced thereby can effectively attain a satisfactory balance between high oxygen permeability and hydrophilicity while achieving an acceptably low concentration of undesirable impurities. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.

Acryloyl materials for molded plastics

In one aspect, the invention relates to silicon-based prepolymers. The disclosed prepolymers exhibit satisfactory solubility in aqueous solutions or hydrophilic solutions and can overcome undesirable shrinkage, expansion, and related problems possessed by conventional silicone monomers and related conventional polymerization techniques by producing hydrogels from a crosslinkable prepolymer. Also disclosed are polymers and molded articles produced from the disclosed prepolymers, which attain a satisfactory oxygen permeability. Also disclosed are methods for producing the disclosed prepolymers. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.

Soluble silicone prepolymers

In one aspect, the invention relates to compositions comprising siloxanyl compounds comprising the structure: or residues thereof. Such compositions can be suitable for producing molded articles, can be excellent in transparency, hydrophilicity, and oxygen permeability, and can have a low modulus of elasticity and/or an excellent optical quality, so as to be suitable for ophthalmic lenses such as contact lenses and intraocular lenses. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.

Siloxanyl materials for molded plastics

This invention provides a process for producing of a silicone compound which includes a synthesis reaction of a silicone compound represented by the following formulas (a) and/or (a'), by reacting a carboxylic acid represented by the following formula (a2) to an epoxy silane represented by the following formula (a1) in presence of a metal salt of the carboxylic acid represented by the general formula (a2), characterized in that the reaction is carried out in presence of 0.05 wt % or more water in said reaction system. Here, A denotes siloxanyl group. Rdenotes a substitutent with 1 to 20 carbons having a polymerizable group. Rto Rrespectively and independently denote hydrogen, a substituted or unsubstituted substitutent with 1 to 20 carbons, or &#x2014;X-A. X denotes a substituted or unsubstituted divalent substitutent with 1 to 20 carbons.

Silicone compound and process for producing the same

The present invention relates to a surface-treated plastic article including a thin layer composed of a polymer complex on the surface. The surface-treated plastic article can be produced by a treatment with at least one kind of aqueous solutions of polymers having a weight average molecular weight of 200 or more. According to the present invention, the plastic articles, such as contact lenses, having superior transparency, wettability, oxygen permeability, and mechanical properties can be provided.

Surface-treated plastic article and method of surface treatment

This invention provides an ophthalmic lens of high tensile elongation (i.e., that does not break easily). It is an ophthalmic lens comprising, as a polymerization component, monomers represented by formula (a) below: 

Ocular lens

Monomers for polymers having high oxygen permeability, high water content and a low modulus of elasticity are provided, and polymers and ophthalmic lenses comprised of said monomers are provided. They are monomers represented by formula (1) or (2) below:X&#x2014;O&#x2014;(CHCHCHO)&#x2014;(CH)&#x2014;A &#x2003;&#x2003;(1) 

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Shiga, Japan

Mitsuru Yokota