Hamamatsu-photonics K.k.

Shizuoka Prefecture

Mitsuo Hiramatsu

Tomonori Kawakami

Tokio Takagi

Gen Takebe

Shinichiro Aoshima

Kazuue Fujita

Tatsuo Dougakiuchi

Naota Akikusa

Bo Li

Tatsuo Fujinami

Isuke Hirano

Kazuyoshi Ohta

Kimihiko Kato

Sakio Suzuki, Deceased

Takeshi Taguchi

Hiroe Sato

Masaru Matsui

Takahiro Makino

A microparticle dispersion liquid manufacturing apparatusincludes a controller, a light source, an irradiation optical system, and a container. A solid objectis contained in and a solventis injected into an interior of the containerto enable attainment of a state where the solid objectis in contact with the solvent. The light sourcerepeatedly outputs pulsed light. By repeatedly irradiating the solventwith the pulsed light from the light source, expansion and contraction of the solventis made to occur repeatedly at the irradiated portion, thereby generating a pressure wave in the solvent, and the pressure wave is made to act on the solid objectto finely pulverize the solid objectand thereby manufacture a microparticle dispersion liquid in which microparticles are dispersed in the solvent. A microparticle dispersion liquid manufacturing method and manufacturing apparatus are thereby realized by which both suppression of impurity formation and an increase in efficiency of microparticle formation can be achieved readily.

Fine-particle dispersion liquid manufacturing method and fine-particle dispersion liquid manufacturing apparatus

A method and an apparatus enabling manufacture of a microparticle dispersion liquid at high efficiency in a short time while suppressing drug degradation, etc., are provided. In a dissolving step, a poorly soluble drug and a dispersion stabilizer are dissolved in a volatile organic solvent in a container. In a fixing step following the dissolving step, the organic solvent, contained in a solution, is eliminated by evaporation, a pellet-form residueis obtained by the organic solvent elimination, and the residueis fixed on an inner wall of the container. In a water injecting step following the fixing step, wateris injected into an interior of the container. In an irradiating step following the water injecting step, laser light, emitted from a laser light source, is irradiated on the residuefixed on the inner wall of the container, and the residueis thereby pulverized and made into microparticles and a microparticle dispersion liquid, constituted of the microparticles being dispersed in the water, is manufactured. The microparticles contain the poorly soluble drug and the dispersion stabilizer.

Microparticles, microparticle dispersion and method and apparatus for producing the same

In a dissolving step, a poorly soluble drug and a dispersion stabilizer are dissolved in a volatile organic solvent. In a fixing step, the organic solvent, contained in a solution obtained in the dissolving step, is removed by evaporation, pellet-form residuesare obtained by the organic solvent removal, and the residuesare fixed on respective bottom surfaces of a plurality of locations of a container. In a water injecting step, wateris injected into each of a plurality of recessesof the container. In an irradiating step, laser light L, emitted from a light irradiating unit, is irradiated simultaneously or successively on the residuesfixed on the respective bottom surfaces of the recessesof the container, and the residuesare thereby pulverized and made into microparticles and a microparticle dispersion liquid, constituted of the microparticles being dispersed in the water, is manufactured.

Microparticle dispersion liquid manufacturing method and microparticle dispersion liquid manufacturing apparatus

A to-be-treated body, which contains raw material particlesof a substance and with which a solventof a to-be-treated liquidis made solid, is used, and a laser light source, which supplies a laser light of a predetermined wavelength to a treatment chamberthat contains the to-be-treated body, is provided to arrange a production apparatusA. The laser light from the laser light sourceis illuminated onto the to-be-treated body to microparticulate the substance in solvent. As the to-be-treated body of solid form, a solidified body, with which wateris solidified by a cooling deviceand the solidified state is maintained by a thermally insulating layer, may be used. Or, as the to-be-treated body, a gel body, with which the solvent is gelled, may be used. The substance can thereby microparticulated efficiently by photo-pulverization.

Microparticles, microparticle production method, and microparticle production apparatus

With this invention, in a nanoparticle production method, wherein nanoparticles are produced by irradiating a laser light irradiation portionof a to-be-treated liquidwith a laser light, in which suspended particles are suspended, to pulverize the suspended particles in laser light irradiation portion, laser light irradiation portionof to-be-treated liquidis cooled. In this case, by the cooling of to-be-treated liquid, the respective suspended particles are cooled in their entireties. When the portionof this to-be-treated liquidis irradiated with the laser light, the laser light is absorbed at the surfaces of the suspended particles at portion. Since to-be-treated liquidis cooled during this process, significant temperature differences arise between the interiors and surfaces of the suspended particles and between the surfaces of the suspended particles and the to-be-treated liquid at laser light irradiation portion, and highly efficient nanoparticulation is realized.

Nanoparticle production method and production device and nanoparticle preservation method

An apparatusA for processing carbon nanotubes (CNTs) includes: a processing chamberfor housing to-be-processed liquidwith CNT raw materialto be fragmented being suspended in a solvent; and a pulse irradiation light sourcefor applying pulse light having a predetermined wavelength for fragmentation of the CNTs in the solventto the to-be-processed liquidhoused in the processing chamber. This achieves a method and apparatus for processing carbon nanotubes that can fragment CNTs efficiently, and carbon nanotube dispersion liquid and carbon nanotube powder produced by the same.

Carbon nano tube processing method, processing apparatus, and carbon nano tube dispersion liquid, carbon nano tube powder

A production apparatus which includes: a treatment chamber, containing a to-be-treated liquid, made up of water, which is a solvent, and raw material particles of a substance; a laser light source, illuminating laser light for microparticulation onto the to-be-treated liquid; an ultrasonic transducer, irradiating ultrasonic waves for preventing aggregation of microparticles; and a controlling device, controlling the laser light illumination by the laser light source and the ultrasonic wave irradiation by the ultrasonic transducer. A vibration amplitude of the treatment chamber is monitored by means of a microphone and a vibration amplitude measuring device to set the frequency of the ultrasonic waves to a resonance vibration frequency. A microparticle production method and production apparatus that enable substances to be microparticulated efficiently by photo-pulverization, and microparticles are thus realized.

An absorbance measuring pipette includes a pipette and a pipette adapter. The pipette adapter has a pipette attachment portion for receiving the front end of the pipette and a tip attachment portion for attaching a tip and is attachable between the pipette and the tip. The pipette adapter has an inner space continuous with respective internal spaces of the pipette and tip upon attachment. The pipette adapter includes a test light introducing window for introducing a test light into the inner space from outside and a reflecting mirror for reflecting toward the sample suction port of the tip by way of an opening in the tip attachment portion the test light introduced into the inner space through the test light introducing window.

Pipette adapter, absorbance measuring pipette, tip, absorbance measuring apparatus, and absorbance measuring

An apparatus including: a sprayer for inoculating a microbe on a first division divided from at least one sample of a plant to be examined; sample leaving device for leaving a second division divided from the sample not inoculated with the microbe and the first division inoculated with the microbe, for a predetermined period of time under a predetermined condition; first and second photodetector for respectively measuring the quantities of luminescence emitted from the first and second divisions which have been left standing by the sample leaving device; and a computer for comparing the quantities of the luminescence measured by the first and second photodetector, thereby to examine the resistance or susceptibility of the plant to the microbe.

Methods and apparatuses for examining pathogen resistance of plant, for

The liquid treating method according to the present invention introduces a bubble into liquid phase and applies vibration waves, such as ultrasonic waves, from each sides of the bubble. Collision of the vibration waves with the bubble imparts the compression pressure to the bubble. This effect is used to dissolve a gas forming the bubble into the liquid phase or to improve liquid quality of this liquid phase.

Liquid treating method and liquid treating apparatus

The present invention provides an optical device according to this invention comprising a light transmitting optical member of a high molecular material containing mobile ions, and a pair of electrodes formed on surfaces of the optical member, a required potential difference being provided between the electrodes so as to cause ion conduction in the optical member and to reversibly vary a refractive index of the optical member. According to this invention, a refractive index is reversibly varied due to ion conduction, whereby the modulation of a transmitted beam or a reflected beam by the optical device can be reversibly controlled.

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Hamamatsu, Japan

Mitsuo Hiramatsu