Sansho Co., Ltd.

Eisai Company, Limited

Takasago International Corporation

Sekisui Kagaku Kogyo Kabushiki Kaisha

Mitsuhiro Yoshida

Yoshio Ishino

Hiroyuki Fujimori

Yutaka Morita

Masayoshi Kasai

Shigemitsu Ohsawa

Akira Sasaki

Masanori Kayano

Yoshifumi Yuasa

Toyohiko Kobayashi

Masato Azuma

Shigemitsu Osawa

Tsutomu Negama

Keiji Ohmori

Hidenori Asakawa

Noriko Konita

A pharmacological composition for percutaneous administration to a human patient comprises a pharmacologically effective amount of eperisone, a salt thereof, tolperisone or a salt thereof, a water-swellable crosslinked polyvinylpyrrolidone and a base carrier, and exhibits improved percutaneous absorption.

Percutaneously absorbable crosslinked polyvinylpyrrolidone eperisone or

Preparation for endermism containing dopamine derivatives

A pharmaceutical preparation for the percutaneous administration comprises eperisone or tolperisone, including salts thereof, and a monoglyceride of an aliphatic acid having 8 to 12 carbon atoms or/and an ester of lactic acid with an aliphatic alcohol having 12 to 18 carbon atoms. It is improved in the percutaneous absorption.

Pharmaceutical preparation for percutaneous administration containing

A pharmaceutical composition comprises (a) a pharmacologically effective amount of bunazosin or a pharmacologically acceptable salt thereof and (b) a monoglyceride of a fatty acid having 8 to 12 carbon atoms and/or a lactic acid ester of an aliphatic alcohol having 12 to 18 carbon atoms and is improved in percutaneous administration. ##STR1##

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Saitama, Japan

Mitsuhiro Yoshida