Daiichi Sankyo Company, Limited

Mitsuhiro Yamaguchi

Takahiro Yamaguchi

Keiko Suzuki

Akihiro Tamura

Tomohiro Nishizawa

The present invention provides a compound having excellent regulating action on blood lipid level. The present invention provides a compound represented by the following general formula (I) or a pharmacologically acceptable salt thereof, etc., wherein A represents a 5-membered nitrogen-containing aromatic heterocyclyl group; Rrepresents COOH or the like; each Rrepresents an alkyl or the like; each Rrepresents an optionally substituted phenyl, an optionally substituted phenylalkyl, or the like; m represents 0, 1, 2, or 3; n represents 0 or 1; each of R, R, R, and Rrepresents H, an alkyl, or the like; and B represents an optionally substituted naphthyl, an optionally substituted aromatic heterocyclyl, or a group represented by the following formula (II) wherein each of Band Brepresents an optionally substituted phenyl or an optionally substituted aromatic heterocyclyl. 

Nitrogen-containing aromatic heterocyclyl compound

The present invention provides a compound having excellent regulating action on blood lipid level that is represented by the following general formula (I) or a pharmacologically acceptable salt thereof, wherein, in one embodiment, A represents a 5-membered nitrogen-containing aromatic heterocyclyl group; Rrepresents COOH; each Rrepresents an alkyl; each Rrepresents an optionally substituted phenyl, an optionally substituted phenylalkyl; m represents 0, 1, 2, or 3; n represents 0 or 1; each of R, R, R, and Rrepresents H, an alkyl; and B represents an optionally substituted naphthyl, an optionally substituted aromatic heterocyclyl, or a group represented by the following formula (II) wherein each of Band Brepresents an optionally substituted phenyl or an optionally substituted aromatic heterocyclyl. 

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Tokyo, Japan

Mitsuhiro Yamaguchi