Hamamatsu-photonics K.k.

Osaka Prefectural Hospital Organization

Hamamatsu University School of Medicine

National University Corporation Hamamatsu University School of Medicine

Mitsuharu Miwa

Takahiro Shikayama

Yutaka Tsuchiya

Osamu Ishikawa

Kazumasa Hirawake

Terumasa Yamada

Kunihito Gotoh

Tsuneyuki Urakami

Takayuki Sato

Akira Takahashi

Yukio Ueda

Yutaka Yamashita

Shunsuke Matsuda

Naoki Unno

Takayuki Miyashita

Yoshimasa Hattori

Kenjiro Hasegawa

Toshiyuki Kitai

An observation device is an observation device observing an observation target and includes: an emission light source that generates emission light; a projection light source that generates projection light; a scanning mirror that scans the emission light and the projection light toward the observation target along the same optical path; a light guide optical system that guides detection target light generated in the observation target in accordance with emission of the emission light without it passing through the scanning mirror; an optical detector that detects the detection target light guided by the light guide optical system; and a control unit that controls an intensity of the projection light on the basis of a result of the detection of the detection target light.

Observation device and observation method

Cover for cancer cell observation camera

A fluorescent image acquisition system includes a light emitting device which emits excitation light during ON period and stop the emission of the excitation light during OFF period, an imaging device which outputs ON image data and OFF image data, an input device which sets a coefficient, an image processing unit which creates fluorescent image data and background image data, and an identification unit which identifies fluorescent pixels and non-fluorescent pixels. In order to create a superimposed image, the image processing unit calculates values obtained by summing pixel values of fluorescent pixels of the fluorescent image data and pixel values of fluorescent pixels of the background image data at a ratio of 1:1, as pixel values of the fluorescent pixels and calculates values obtained by multiplying at least pixel values of the non-fluorescent pixels of the background image by the coefficient, as pixel values of the non-fluorescent pixels.

Superimposed image creation apparatus and superimposed image creation method

A fluorescence detection device comprises: a plurality of light sources that apply an excitation light from an outside of a living body toward fluorescent dye previously injected into the living body; and a plurality of detectors that detect fluorescence emitted from the fluorescent dye by the excitation light, and output the detected fluorescence as an electric signal. The plurality of light sources and the plurality of detectors are arranged in at least one line. At least one detector is placed between two light sources, and at least one light source is placed between two detectors.

Fluorescence detection device

A fluorescence viewing device is configured to take a difference between one of an image of a first frame and an image of a second frame output from an imaging device and the other of the first frame image and the second frame image stored in an image storage means, whereby clear observed images can be obtained without influence of background light. In the fluorescence viewing device, an exposure time of a fluorescence image acquisition period and an exposure time of a background image acquisition period are different from each other. Since ON/OFF durations of excitation light also become asymmetric according to the asymmetry of the exposure times, the device can reduce user's feeling of strangeness due to blinking of the excitation light.

Fluorescence viewing device and fluorescence viewing method

The fluorescent light phantom deviceis provided with: a phantom supporthaving fluorescent light phantom containersand; and fluorescent light phantomsandwhich are constituted of a medium that reproduces at least one of light scattering and light absorption of an object to be measured and a fluorescent coloring matter contained in the medium of a predetermined concentration and are stored in the fluorescent light phantom containersand

Fluorescent light phantom device and fluorescent light imaging method

A method of detecting an accessory cancer lesion, comprising an administration step wherein indocyanine green is administered to a living body, an irradiation step wherein a target organ suspected of having cancer is surgically exposed and irradiated with excitation light of indocyanine green, an imaging step wherein a near-infrared fluorescence intensity distribution image from the excited indocyanine green in the target organ is obtained, and an identification step wherein an area having the near-infrared fluorescence in the intensity distribution image, excluding the area detected in preoperative examination or intraoperative macroscopic observation, is identified as an accessory cancer lesion.

Method for detecting cancer using ICG fluorescence method

A sentinel lymph node detecting apparatusincludes: an excitation light source unitthat illuminates an excitation lightonto a living body observation portionincluding a sentinel lymph nodenear a tumor into which a fluorescent dye that emits fluorescence is injected; an optical filterthat transmits a fluorescence image; an image pickup devicethat is integral with excitation light source unitand picks up fluorescence imagetransmitted through optical filter; an adjusting devicethat adjusts the picked-up observation image; and an image displaying devicethat displays the adjusted observation image. Adjusting deviceadjusts at least one of a luminance and a contrast of the observation image. A lymph node detecting apparatus that is simple in apparatus arrangement, is easy to handle, and enables good images to be obtained is thereby realized.

Lymph node detecting apparatus

Growing community of inventors

Hamamatsu, Japan

Mitsuharu Miwa