Kao Corporation

Meito Sangyo Co., Ltd.

Mitsuharu Masuda

Tomihiro Kurosaki

Takashi Imamura

Hiroshi Ito

Shinichiro Omatsu

Katsumi Kita

Yasuo Ishii

Akira Tsunoda

Shigeaki Kato

Yoshitaka Kokusho

Haruya Kato

Motoru Takeda

Yoshiko Chikawa

Takashi Itoh

Noriko Inoue

An alkali metal monoalkylphosphate having a saturated or unsaturated straight-chain or branched hydrocarbon group having from 8 to 32 carbon atoms is described; also described is a process for preparing particles of said alkali metal zinc monoalkylphosphate and cosmetics containing said particles.

Alkali metal zinc monoalkylphosphate, particles thereof, process for

A novel monophosphate and a novel diphosphate prepared by a phosphatidyl transfer reaction of a phospholipid and an alcohol in the presence of phospholipase D are disclosed. The phosphates can independently or together form small and stable liposomes which can include active components therein. Cosmetic compositions comprising these phosphates or liposomes penetrate well into the hair and the skin, and exhibit long-lasting excellent moisture-retaining, beauty, skin-activation effects.

Phosphate, liposome comprising the phosphate as membrane constituent,

A novel phosphoric ester of the formula (I) ##STR1## wherein, Z represents the following radicals ##STR2## useful as modifiers for amino acids, peptides and proteins which are easily decomposable in living bodies.

Phosphoric esters

A novel phosphoric ester represented by the following formula (I): ##STR1## is produced by halogenating the hydroxyl group of a monoalkyl phosphoric acid, reacting the halogenated product with N-benzoyloxycarbonyl serine ester and then removing protecting groups for the carboxyl group and amino group. According to the present production process, the phosphoric ester can be obtained inexpensively at a high yield and high purity. Further, the phosphoric ester has a structure similar to that of the phospholipid and has nitrogen-containing polar groups such as amino group in one molecule, so that it has excellent emulsification ability and moisture keeping function. It is thus useful as emulsifiers, humectants and the like.

Phosphoric ester and process for producing same

A phosphoric ester of the following formula (I): ##STR1## in which R.sub.1 represents a saturated or unsaturated, linear or branched and substituted or unsubstituted hydrocarbon group having from 8 to 32 carbon atoms, R.sub.2, R.sub.3 and R.sub.4 are the same or different and represent a saturated or unsaturated hydrocarbon group having from 1 to 4 carbon atoms, R.sub.5 represents a hydrogen atom, a saturated or unsaturated hydrocarbon group having from 1 to 4 carbon atoms, and n is an integer of from 0 to 50. The above novel phosphoric acid ester has excellent detergent performance with very low irritations to living body. A manufacturing method of the ester is also disclosed. According to the method, the ester can be prepared from inexpensive, readily available starting materials by a simple procedure in high purity and high yield.

Phosphoric esters and method for preparing the same

Growing community of inventors

Wakayama, Japan

Mitsuharu Masuda