Mitsui Chemicals, Inc.

Mitsufumi Wada

Hitoshi Takahashi

Takashi Morishige

Daisuke Mochizuki

Nozomi Takebayashi

Tadashi Araki

Katsuyuki Takahashi

Hiroshi Shimizu

Yoshiko Matsumoto

Koh Amano

Chikara Furusawa

Takashi Hirasawa

Daisuke Miyazawa

Tomokazu Shirai

Junichiro Hirano

Osamu Yoshikawa

Hideki Sawai

Takashi Mimitsuka

Toshihiro Oikawa

Junko Tokuda

Tomonori Hidesaki

Seiichi Watanabe

Hitoki Miyake

Ryota Fujii

Yosuke Higashi

Reiko Abe

Su Sun Chong

Anjali Madhavan

Toshihiro Tateno

Hiroaki Takaku

Miyuki Kawashima

Harutake Yamazaki

Masaki Yabe

Hideki Ouchi

Yusuke Ito

Ayako Endo

Dominik Lukas Jürgen-Lohmann

Tomoyuki Natsuji

Fuminobu Yoshimi

A method of producing THB with improved efficiency is provided. Provided is a method of producing trihydroxybenzene (THB), the method comprising a step of heating a bacterial culture liquid comprising deoxy-scyllo-inosose (DOI) at a high temperature of no lower than 80&#xb0; C. to obtain a product solution comprising trihydroxybenzene (THB).

Trihydroxybenzene production method

A polypeptide includes, in the amino acid sequence of SEQ ID NO: 1 or a similar sequence, at least one specific amino acid substitution on at least one of the 14th, 37th, 209th, 293rd, and 319th amino acid residues from the N-terminal of the amino acid sequence of SEQ ID NO: 1. A polynucleotide, an expression cassette, a vector, and a transformant include a base sequence encoding the amino acid sequence of the polypeptide. A method of producing the polypeptide and a method of producing 2-deoxy-scyllo-inosose are also provided.

Mutant type 2-deoxy-scyllo-inosose synthase

An acetyl-CoA-producing microorganism, which is capable of efficiently synthesizing acetyl-CoA using carbon dioxide, and a substance production method using the same are provided. An acetyl-CoA-producing microorganism including an acetyl-CoA production cycle obtained by imparting at least one type of enzymatic activity selected from the group consisting of malate thiokinase, malyl-CoA lyase, glyoxylate carboligase, 2-hydroxy-3-oxopropionate reductase, and hydroxypyruvate reductase, to a microorganism.

Microorganism having carbon dioxide fixation pathway introduced thereinto

An isopropyl alcohol-producingincludes an isopropyl alcohol production system, wherein an activity of transcriptional repressor GntR is inactivated, and the isopropyl alcohol-producingpreferably further includes a group of auxiliary enzymes having an enzyme activity expression pattern with which isopropyl alcohol production capacity achieved by the inactivation of the GntR activity is maintained or enhanced. A method of producing isopropyl alcohol includes producing isopropyl alcohol from a plant-derived raw material using the isopropyl alcohol-producing. A method of producing acetone includes contacting the isopropyl alcohol obtained by the isopropyl alcohol production method with a complex oxide that includes zinc oxide and at least one oxide containing a Group 4 element, and that is prepared by coprecipitation. A method of producing propylene includes contacting isopropyl alcohol and acetone obtained by the production method with a solid acidic substance and a Cu-containing hydrogenation catalyst as catalysts.

Isopropyl alcohol-producing bacterium having improved productivity by GntR destruction

Disclosed is anproducing 2-deoxy-scyllo-inosose (DOI), which, from a sucrose non-PTS gene group, has at least a sucrose hydrolase (CscA)-encoding gene and which is provided with a DOI production system or has an enhanced DOI production system. Thepreferably further includes a system to enhance sugar uptake capacity. There is also disclosed a method of producing DOI from a plant-derived raw material containing sucrose by using the

Bacterium producing 2-deoxy-scyllo-inosose (DOI) and method of producing 2-deoxy-scyllo-inosose (DOI) by using same

Hydroxycarboxylic acids are produced by using a microorganism that is improved in ability to produce nicotinamide adenine dinucleotide by deleting, mutating or substituting nadR gene in the microorganism or introducing a gene encoding nicotinic acid phosphoribosyltransferase.

Method for producing hydroxycarboxylic acid by enhancing synthesis of coenzyme

The present invention provides an isopropyl alcohol-producingthat includes at least a sucrose hydrolase gene that belongs to a sucrose non-PTS gene group, and an imparted or enhanced isopropyl alcohol production system, and an isopropyl alcohol production method of producing isopropyl alcohol from a sucrose-containing plant-derived raw material using the isopropyl alcohol-producing

Isopropyl alcohol-producing bacterium and method for producing isopropyl alcohol

The invention provides: an isopropyl alcohol-producing bacterium which has an acetoacetate decarboxylase activity, an isopropyl alcohol dehydrogenase activity, a CoA transferase activity and a thiolase activity having been imparted thereto and is capable of producing isopropyl alcohol from a plant-derived material; a method of producing isopropyl alcohol whereby isopropyl alcohol is produced from a plant-derived material by using this isopropyl alcohol-producing bacterium; and an apparatus therefor.

Isopropyl alcohol-producing bacterium and method of producing isopropyl alcohol using the same

An isopropyl alcohol-producingequipped with an isopropyl alcohol production system, having at least one enhanced enzyme activity selected from the group consisting of an enhanced malate dehydrogenase activity, an enhanced NAD(P)transhydrogenase (AB-specific) activity, and an enhanced thiolase activity, and an isopropyl alcohol producing method including producing isopropyl alcohol from a plant-derived raw material using the isopropyl alcohol-producing

Highly productive isopropyl alcohol-producing bacterium

Hydroxycarboxylic acids are produced by using a microorganism that is improved in ability to regenerate oxidized-type nicotinamide adenine dinucleotide by being provided with an enhanced NADH dehydrogenase function by introducing a gene encoding NADH dehydrogenase into a microorganism.

Method for producing hydroxycarboxylic acid by regenerating coenzyme

An object of the invention is to produce a microorganism which yields high amounts in a short time of a hydroxycarboxylic acid reduced in impurity content. This invention further provides a process for producing a hydroxycarboxylic acid, including glycolic acid, using the microorganism. This process enables a hydroxycarboxylic acid having high purity to be supplied at low cost.

Process for producing hydroxycarboxylic acid

The present invention provides: a lactic acid-producingcomprising at least one gene of a sucrose non-PTS gene group, including at least a sucrose hydrolase gene, provided that a combination of a repressor protein (cscR), a sucrose hydrolase (cscA), a fructokinase (cscK) and a sucrose permease (cscB) and a combination of a sucrose hydrolase (cscA), a fructokinase (cscK) and a sucrose permease (cscB) are excluded, wherein the lactic acid-producingcomprises a lactic acid production enhancing system provided by genetic recombination; and a lactic acid production method including producing lactic acid from a plant-derived sucrose-containing raw material by using the lactic acid-producing

Method for producing lactic acid from plant-derived raw material, and lactic-acid-producing bacterium

The present invention provides: a lactic acid-producingincluding an enzymatic activity of at least one NAD-dependent lactate dehydrogenase and an enzymatic activity of at least one NAD-independent lactate oxidoreductase, both of which are enhanced so as to decompose one of D-lactic acid or L-lactic acid and to produce the other one of D-lactic acid or L-lactic acid; and a lactic acid production method using the lactic acid-producing

Bacterium capable of producing lactic acid, and method for producing lactic acid

Growing community of inventors

Chiba, Japan

Mitsufumi Wada