The State University of New York

Princeton University

Other

Mitchell S Albert

William Happer

Gordon D Cates, Jr

Bastiaan Driehuys

Brian Saam

Dilip Balamore

Arnold Wishnia

Jeffrey J Spiegelman

Arvind K Venkatesh

A method of imaging a spatial distribution of a noble gas by nuclear magnetic resonance spectrometry includes detecting a spatial distribution of at least one noble gas by NMR spectrometry and generating a representation of said spatial distribution of the noble gas. The noble gas is selected from noble gas isotopes having nuclear spin, preferably Xenon-129 and/or Helium-3. The noble gas is at least thermally or equilibrium polarized and is preferably hyperpolarized, most preferably hyperpolarized by optical (laser) pumping in the presence of an alkali metal or by metastability exchange. The generation of the representation of the noble gas spatial distribution includes at least one dimension, preferably 2 or 3 dimensions of the spatial distribution. The noble gas may be imaged according to the invention in chemical or biological systems, preferably in a human or animal subject or organ system or tissue thereof. Also, apparatus for nuclear magnetic resonance imaging of the spatial distribution of at least one noble gas includes means for imaging a noble gas by NMR spectrometry and means for providing and/or storing imageable quantities of a noble gas, preferably hyperpolarized Xenon-129 and/or Helium-3. Also, a medical composition includes a medically acceptable bifunctional gas effective for in vivo anesthesiological and NMR imaging functions, including at least one noble gas, preferably hyperpolarized Xenon-129 and/or Helium-3.

Magnetic resonance imaging using hyperpolarized noble gases

The present invention is directed to a procedure for recycling used gasses and to devices that can be use to accomplish this recycling.

Method and apparatus for delivering and recovering gasses

Magnetic resonance imaging using Hyperpolarized noble gases

Growing community of inventors

Shoreham, NY, United States of America

Mitchell S Albert