Valentx, Inc.

Merit Medical Systems, Inc.

Mitchell Dann

Lee Guterman

Jonathan Kagan

Joshua Butters

Paul Swain

Greg Fluet

James Wright

T Wade Fallin

Gerard Von Hoffmann

Thomas Baldwin

James Balliro

Cole Chen

Christopher Paul Swain

John C Hancock

Judson A Herrig

Richard Thomas

Josiah E Verkaik

James Leary

David Carr-Locke

Sayeed Ikramuddin

Bobby Griffin

Stephen Hohmann

An apparatus and method are provided to treat a stenosis. A delivery device is provided that has an elongate tubular member coupled therewith. The elongate tubular member has an outside surface that is configured to prevent adherence of in vivo matter. The tubular member has a proximal end and a distal end and is reinforced along its length to maintain open lumen under a transverse load. The tubular member is placed in the vasculature such that the distal end of the elongate tubular member is disposed distal of a stenosis. The proximal end of the elongate tubular member is disposed inside the vessel, preferably at a location proximal of the stenosis. Thereafter, after a therapeutic period, the elongate tubular member is removed intact.

Implantable and removable customizable body conduit

The present invention provides devices and methods for attachment of an endolumenal gastrointestinal device, such as an artificial stoma device, a gastrointestinal bypass sleeve or other therapeutic or diagnostic device, within a patient's digestive tract. In one application of the invention, an endolumenal bypass sleeve is removably attached in the vicinity of the gastroesophageal junction to treat obesity and/or its comorbidities, such as diabetes. The bypass sleeve may be at least partially deployed by eversion.

Devices and methods for endolumenal gastrointestinal bypass

Apparatus and methods are described for treatment of morbid obesity using minimally invasive techniques. The apparatus includes a system of components that may be used separately or in combination for effectively reducing stomach volume, bypassing a portion of the stomach and/or small intestines, reducing nutrient absorption in the stomach and/or small intestines and/or depositing minimally or undigested food farther than normal into the intestines, thereby stimulating intestinal responses. The components described include an artificial stoma device, a gastric sleeve device, an intestinal sleeve device, a combined gastrointestinal sleeve device and permanent and detachable attachment systems. Also described are devices for delivering and deploying the components of the system.

Apparatus and methods for treatment of morbid obesity

Methods are disclosed for replaceable attachment of an endoluminal gastrointestinal device, such as an artificial stoma device, a gastrointestinal bypass sleeve device or an attachment cuff, within a patient's digestive tract for treatment of obesity.

Methods of replacing a gastrointestinal bypass sleeve for therapy adjustment

Disclosed herein are elongate flexible medical devices which are capable of axial elongation through a mechanism of eversion or toposcopic expansion. In general, this may be accomplished by providing a flexible tubular body having a proximal end and a distal end. Retraction of the distal end in a proximal direction through the tubular body inverts the tubular body upon itself, causing an axial shortening of an overall length of the tubular device. An original length of the tubular device can be restored by coupling a pressurized media to the proximal end of the tubular device. If the distal end of the tubular device is temporarily restricted or closed, the pressurized media causes the distal end of the tubular device to travel distally until a full length of the tubular device has been restored.

Methods for toposcopic sleeve delivery

Disclosed herein are systems and methods for attaching or maintaining the position of a therapeutic or diagnostic device in a body lumen, such as the GI tract without necessarily requiring any penetrating attachments through any body walls. The system can include at least two elements: a proximal orientation element and a distal support element. The proximal orientation element can be configured to reside at least partially within the esophageal lumen and the distal support element can be configured to reside in the stomach, such as along the greater curve of the stomach. An intragastric support system can have a first configuration in which the long axis of the proximal orientation element is substantially parallel and/or substantially coaxial with the long axis of the distal support element, and a second configuration in which the long axis of the proximal orientation element is not substantially coaxial with the long axis of the distal support element. The second configuration can thus advantageously retain the intragastric support system in place and prevent unwanted proximal migration of the distal support element into the esophagus or distal migration into the intestine.

Methods and devices for intragastric support of functional or prosthetic gastrointestinal devices

Disclosed herein are elongate flexible medical devices which are capable of axial elongation through the mechanism of eversion or toposcopic expansion. In general, this may be accomplished by providing a flexible tubular device having a proximal end and a distal end. Retraction of the distal end in a proximal direction through the tubular body inverts the tube upon itself, causing an axial shortening of the overall length of the device. The original length of the device can be restored by coupling a pressurized media to the proximal end of the sleeve. If the distal end of the sleeve is temporarily restricted or closed, the pressurized media causes the distal end of the sleeve to travel distally until the full length of the sleeve has been restored.

Toposcopic access and delivery devices

The present invention provides devices and methods for attachment of an endoluminal gastrointestinal device, such as an artificial stoma device, a gastrointestinal bypass sleeve device or an attachment cuff, within a patient's digestive tract for treatment of obesity.

Devices and methods for attaching an endolumenal gastrointestinal implant

The present invention provides devices and methods for attachment of an endolumenal gastrointestinal device, such as an artificial stoma device, a gastrointestinal bypass sleeve or other therapeutic or diagnostic device, within a patient's digestive tract. In one application of the invention, an endolumenal bypass sleeve is removeably attached in the vicinity of the gastroesophageal junction to treat obesity and/or its comorbidities, such as diabetes. The bypass sleeve may be at least partially deployed by eversion.

Attachment cuff for gastrointestinal implant

Disclosed herein is a method of treating a patient, that includes providing a gastrointestinal sleeve device having an elongate tubular body, with a proximal opening and a distal opening; and positioning the gastrointestinal sleeve device in the patient's digestive tract such that the proximal opening of the tubular body is positioned at the native gastroesophageal junction to receive ingested food and liquids from the patient's esophagus and the distal opening of the tubular body is positioned in the patient's jejunum. The tubular body can then be attached near its proximal opening to the patient at the native gastroesophageal junction.

Methods of transmural attachment in the gastrointestinal system

Attachment system for transmural attachment at the gastroesophageal junction

Methods and devices for gastrointestinal stimulation are disclosed. In one embodiment, disclosed is an electrical stimulator device that includes a circuit board and a battery contained within a base housing; a conduction element; and at least one electrode. In some embodiments, the stimulator base housing can be directly attached to a wall of a body lumen. In other embodiments, the stimulator base housing can be attached to a cuff or a sleeve device. In still other embodiments, one or more elements of the system are free-floating within the GI tract. The devices can be delivered endoscopically, and in some embodiments toposcopically.

Growing community of inventors

Wilson, WY, United States of America

Mitchell Dann