Other

Standard Biotools Canada Inc.

Mitchell A Winnik

Bansi Lal Kaul

Vladimir I Baranov

Mark Nitz

Xudong Lou

Jianping Lu

Xijia Gu

Ian Manners

Yizeng Ni

Jean-Christophe Graciet

Mei Li

Zhen Pang

Frederic Tronc

Element tags based on novel metal-polymer conjugates are provided for elemental analysis of analytes, including ICP-MS. A polymer backbone is functionalized to irreversibly bind metals that are selected prior to use by the user. The polymer is further functionalized to attach a linker which allows for attachment to antibodies or other affinity reagents. The polymer format allows attachment of many copies of a given isotope, which linearly improves sensitivity. The metal-polymer conjugate tags enable multiplexed assay in two formats: bulk assay, where the average biomarker distribution in the sample is diagnostic, and single cell format to distinguish a rare (for example a diseased) cell in a complex sample (for example, blood).

Polymer backbone element tags

This invention relates to copolymer compositions having pigment like properties, comprising a fluorescent or non-fluorescent dye attached to a polymer chain by a spacer having a chain length of Cor longer. The invention also provides for new mono- and difunctional dye monomers comprising a polymerizable group attached to a dye moiety by a spacer of a chain length of Cor longer. The polymer pigments provide excellent properties, especially high temperature stability and easy applicability as colorant in different standard polymers.

Copolymer composition having pigment like properties

A pressure sensor comprising a stable polymer having a backbone containing nitrogen and one or more of sulfur or phosphorous, and including a phosphorescent dye agent.

Phosphorescent oxygen sensors

Growing community of inventors

Toronto, Canada

Mitchell A Winnik