Korea University Research and Business Foundation

Kyungpook National University Industry-Academic Cooperation Foundation

Miseon Ryu

Jong-Ho Kim

Ji-Young Park

Jong Hwa Jung

Sugyeong Kwon

Minseon Jeong

Chung Ho Kim

Seung Cheol Choi

Soon Jun Hong

Hyung Joon Joo

Chan-Sik Yang

The present invention relates to a novel N-acylurea derivative and the use thereof for the prevention or treatment of cardiovascular disease, and more particularly to a novel N-acylurea derivative, a pharmaceutical composition for prevention or treatment of cardiovascular disease, which contains the N-acylurea derivative as an active ingredient, and a method of preparing the N-acylurea derivative. The N-acylurea derivative according to the present invention can inhibit platelet aggregation by inhibiting the activity of talin in the intracellular matrix, and thus can be useful for the prevention or treatment of cardiovascular disease.

N-acylurea derivative and composition comprising same for prevention or treatment of cardiovascular disease

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Gyeongsangnam-do, South Korea

Miseon Ryu